What Do You Make of This?: redjournal... - Advanced Prostate...

Advanced Prostate Cancer

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What Do You Make of This?

ADTMan profile image
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redjournal.org/article/S036...

I had a Gleason 4 tumor (2 cm x 1 cm) with a PSA in the 20's. Is this saying that targeted treatment with no or limited ADT would have been sufficient, especially if HDR brachytherapy were used with IMRT?

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Tall_Allen profile image
Tall_Allen

Nope. It's just saying that results of external beam radiation (EBRT) are improved with a little extra boost dose to any MRI-detected tumors in the prostate. (It confirms the FLAME RCT.)

prostatecancer.news/2021/01...

It doesn't address ADT (everyone in the trial had at least some ADT), which others have shown is required for 27 months when only EBRT is used for high-risk patients.

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