Good news-latest Axumin PET results

[HopingForTheBest1]

Originally diagnosed in June 2018 with stage 4 CRPC metastasis to pelvic bone, and BRCA2+ in December 2018. Have had several treatments including robotic prostatectomy (November 2018), Firmagon (one month), Lupron, Eligard (ongoing), Zytiga/Prednisone (6 months), Provenge immunotherapy, Xgeva (ongoing) and Olaparib (ongoing). PSA has been undetectable for the past year.

I had my initial Axumin PET scan a year ago, with a lack of conclusive findings as there was no other such scan to compare against. My second scan was done in March, 2020, and the results were as follows-

*images of the visualized head without evidence of malignancy

*periclavicular region, anterior chest wall, breast and axillary regions without evidence of malignancy

*mediastinum and lung parenchyma without evidence of malignancy

*liver and spleen, region of adrenals and pancreas without evidence of malignancy

*region of the prostate fossa generally unremarkable on PET; subtle uptake is seen in the penile bulb region of the very low level and considered unrelated to malignancy

*bilateral scattered small inguinal femoral nodes with traces of uptake, consider typically nonmalignant

*globally, there is notable improvement in the skeleton on current imaging essentially resolved activity in prior lesions; overall suspect a positive treatment effect

*resolved prior activity in the right side of the sacrum, and left iliac disease

*healed metastases in the left side of sacrum

*complete resolution of prior intense uptake in the right symphysis pubis; activity right ischial region with more pronounced sclerotic healing; activity right ischial region; activity in right ischial disease currently no uptake and extensive sclerotic healing

*globally, all areas with pronounced positive response to treatment, demonstrating additional further sclerotic healing. A very good response in the skeleton. Currently no areas of abnormal uptake to suggest active disease. Areas of prior uptake currently replaced with progressing sclerotic healing effect

I could not have asked for a better report and outcome! No "cure" for the foreseeable future, but hoping to keep this up for a long time.

[Tub111]

So happy for you!!! Keep up the good fight! 🙏❤️

Sheri

[Jmr11820]

What a great feeling that must be! Congratulations!

[Vitaminlover]

Wonderful news!

[VioS]

I am so happy to hear such good news for you .Maybe I should go your route and ask my urologist about the genetic testing. I don’t have an oncologist yet .Now I am just a month after my RP and waiting to get a PSA done in a month or so.

[HopingForTheBest1 in reply to VioS]

Definitely worth asking. When you look for an oncologist make sure to research as much as possible. Know your treatment options. Your life is in their hands. Also get second opinions. Wishing you luck.

[j-o-h-n in reply to VioS]

Ask here for MO recommendations in your area (location) asap...

Vio..... Viiiiooooo, come mr tallyman tally me bananas.....♪♪♪

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 04/23/2020 6:39 PM DST

[Pleroma]

Excellent results! Were you in a clinical trial for the Olaparib?

[HopingForTheBest1 in reply to Pleroma]

No. My Oncologist applied for and was able to get me "off label use" outside of any trials.

[Hidden]

So happy for you. Feel the joy of this moment - happy and safe and healthy.

[SPEEDYX]

That's what we like to hear!!!..All the best in your journey.

[Lyubov]

Very happy for you. Hubby's genetic test fell to back burner because other health issue intervened. As soon as he recovers from that we'll get back to it. Obviously it makes a big difference to know the results.

All best wishes to you!

[HopingForTheBest1]

Thanks. Same to you and husband.

[j-o-h-n in reply to HopingForTheBest1]

Nothing but the best.........

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 04/23/2020 6:40 PM DST

[No17]

Good for you!

[Moespy]

Great news! Do you mind sharing who your doctors are?

[HopingForTheBest1 in reply to Moespy]

I live in NJ, and am being treated at CINJ. Oncologist is Biren Saraiya. Surgeon is Isaac Kim.

[Moespy in reply to HopingForTheBest1]

Thank you for that information. It appears that your team is progressive and not afraid to look outside SOC. Would you agree?

[HopingForTheBest1]

Yes, although there was mixed opinion regarding Provenge. I had seen recent research that showed the sooner one gets treated the better the outcome. I ultimately decided to go for it; no regrets.

[Moespy in reply to HopingForTheBest1]

Thank you very much for the info and the feedback.

[tallguy2]

Congrats on the great results!

[dorke]

Very good news, congratulations !!

As a BRCA2 mutation carrier myself,it gives me hope

[HopingForTheBest1 in reply to dorke]

Thank you. We post in this forum to provide hopefully useful info. We are in this fight together.

I looked back at your posts. Didn't find any mention about considering PARP inhibitor. As a fellow BRCA2+ patient, I definitely recommend you discuss it with your Oncologist. Best wishes.

[Bodysculpture]

So happy for you

That's an amazing result

Keep on keeping on