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Muscle Mass Loss ADT, Firmagon Or Zytiga? Any Studies on MML on ADT

Are there any studies noted what treatments cause more muscle loss than others… Which is worse for muscle loss Firmagon or Zytiga?
Are there any studies noted what treatments cause more muscle loss than others… Which is worse for muscle loss Firmagon or Zytiga?
Shorehousejam profile image
Shorehousejam
in Advanced Prostate Cancer
3 months ago

Next Steps?

His statements were: 1) wait and watch to see if it spreads anywhere else. 2) Start Firmagon ADT again. 3) Start Firmagon ADT and do 25 radiation treatments of that area of my body. 4) Do focused radiation of the area where the lymph nodes are. He had reasons for all 4.
His statements were: 1) wait and watch to see if it spreads anywhere else. 2) Start Firmagon ADT again. 3) Start Firmagon ADT and do 25 radiation treatments of that area of my body. 4) Do focused radiation of the area where the lymph nodes are. He had reasons for all 4.
OldChappy profile image
OldChappy
in Advanced Prostate Cancer
1 month ago

Lupron or Firmagon after Orgovyx

My RO is fine giving me one month shots of Lupron or Firmagon.   He thinks they will have minimal effect on recovery.  I could probably pay for the pills, but six grand is six grand.  The Firmagon is an antagonist and the same mode of action as Orgovyx.   That makes me lean toward it as a shot.   
My RO is fine giving me one month shots of Lupron or Firmagon.   He thinks they will have minimal effect on recovery.  I could probably pay for the pills, but six grand is six grand.  The Firmagon is an antagonist and the same mode of action as Orgovyx.   That makes me lean toward it as a shot.   
Mike404 profile image
Mike404
in Prostate Cancer Network
20 days ago
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Alarming visit with Oncologist. How do we handle this? Another extremely time sensitive situation we were thrown into

Father started Firmagon Injections on Nov 10th and radiation Dec 12th (yesterday). 1. Urologist started him on firmagon on Nov 10th to prevent spread while awaiting further treatment. It seems to have worked.. CT Scan update today was that no far spread.
Father started Firmagon Injections on Nov 10th and radiation Dec 12th (yesterday). 1. Urologist started him on firmagon on Nov 10th to prevent spread while awaiting further treatment. It seems to have worked.. CT Scan update today was that no far spread.
FormulaRob profile image
FormulaRob
in Advanced Prostate Cancer
2 months ago

Suspecting neuroendrocrine soft cell prostate cancer

He already had undergone firmagon abiraterone , lu177 . Thanks
He already had undergone firmagon abiraterone , lu177 . Thanks
Ankitsharma021290 profile image
Ankitsharma021290
in Advanced Prostate Cancer
29 days ago

Now I'm really confused

Im concerned that the Firmagon failed after just 4 months and now I'm seeing xtandi seemingly stalling and I'm taking steps to plan out my next move. 
Im concerned that the Firmagon failed after just 4 months and now I'm seeing xtandi seemingly stalling and I'm taking steps to plan out my next move. 
GSDF profile image
GSDF
in Advanced Prostate Cancer
3 months ago

Rather quick failing of Firmagon

Firmagon brought it down to 13 but failed after just 6 months. Now on Orgovyx and Xtandi. My concern is the relative quick failing of Firmagon. Would this indicate that the Xtandi will also fail quickly? Thanks!
Firmagon brought it down to 13 but failed after just 6 months. Now on Orgovyx and Xtandi. My concern is the relative quick failing of Firmagon. Would this indicate that the Xtandi will also fail quickly? Thanks!
GSDF profile image
GSDF
in Advanced Prostate Cancer
6 months ago

Finally makes sense

I started Firmagon about a year ago with great results for 5 months and then added Xtandi....Side effects from both were minimal due to weight training in gym 3x a week and aerobic running off days.
I started Firmagon about a year ago with great results for 5 months and then added Xtandi....Side effects from both were minimal due to weight training in gym 3x a week and aerobic running off days.
GSDF profile image
GSDF
in Advanced Prostate Cancer
2 months ago

PSA is relatively low, but I am having bone pain in my pelvis and spine

Started out with Firmagon and 5 rounds of Taxotere. PSA went to 0.1. We switched from Firmagon to Orgovyx in August 2021. In January 2022 we added Nubeqa. PSA has held pretty steady around 0.1 - 0.3.
Started out with Firmagon and 5 rounds of Taxotere. PSA went to 0.1. We switched from Firmagon to Orgovyx in August 2021. In January 2022 we added Nubeqa. PSA has held pretty steady around 0.1 - 0.3.
Pianodude profile image
Pianodude
in Advanced Prostate Cancer
4 months ago

PSA increase in less than two months of ADT

He was given Firmagon (Degarelix 240mg) on Dec.2. His PSA dropped to 500 on Dec.28. He's been much better since. January 2: Second dose of Firmagon 80mg. We finally got to see an oncologist two days ago, who recommends Zytiga and Chemo concurrently as soon as possible.
He was given Firmagon (Degarelix 240mg) on Dec.2. His PSA dropped to 500 on Dec.28. He's been much better since. January 2: Second dose of Firmagon 80mg. We finally got to see an oncologist two days ago, who recommends Zytiga and Chemo concurrently as soon as possible.
Sissel25 profile image
Sissel25
in Advanced Prostate Cancer
3 days ago

What is Next? Dx 07/2022 PSA 942.40 current 0.24 Starting 5th cycle of Docetaxel Chemotherapy, Discuss Radical Prostatectomy or Radiation?

Currently on Firmagon, Zytiga with Prednisone, Vit D, Metformin Will be starting Otelza for very severe made worse by ADT plaque psoriasis From what I heard there are some clinical trials and cancer centers/hospitals conducting surgery, radical prostatectomy for men with advanced metastatic prostate
Currently on Firmagon, Zytiga with Prednisone, Vit D, Metformin Will be starting Otelza for very severe made worse by ADT plaque psoriasis From what I heard there are some clinical trials and cancer centers/hospitals conducting surgery, radical prostatectomy for men with advanced metastatic prostate
Shorehousejam profile image
Shorehousejam
in Advanced Prostate Cancer
2 months ago

Xtandi vs. Zytiga

Firmagon for a month, then Lupron since. Also Zytiga w/Prednisone. PSA went down to 1. Two months ago my liver enzymes started to rise. Took a one month vacation from Zytiga. Liver enzymes came back to normal. Resumed Zytiga 2 weeks ago at half dosage.
Firmagon for a month, then Lupron since. Also Zytiga w/Prednisone. PSA went down to 1. Two months ago my liver enzymes started to rise. Took a one month vacation from Zytiga. Liver enzymes came back to normal. Resumed Zytiga 2 weeks ago at half dosage.
Rusty31 profile image
Rusty31
in Advanced Prostate Cancer
3 months ago

A few questions and advice desperately needed here , only one shot at this please help

Now that my father is on firmagon, if they don’t do the new CT scan and bone scan until 3 weeks from now is that okay? Assuming firmagon will prevent cancer spreading any further meaning the 3 week wait is nothing to be concerned about ? 3. If they decide he is not curable.
Now that my father is on firmagon, if they don’t do the new CT scan and bone scan until 3 weeks from now is that okay? Assuming firmagon will prevent cancer spreading any further meaning the 3 week wait is nothing to be concerned about ? 3. If they decide he is not curable.
FormulaRob profile image
FormulaRob
in Advanced Prostate Cancer
2 months ago

I'm 84 and diagnosed with PC 5 months ago. I was told I had High Risk Localized PC with a Gleason score of 8.

I have not consented yet because I was told at the outset that they favored Firmagon because Lupron caused a short-term rise in testosterone. My concern is that Lupron might cause a flare up even though I taken 4 months of Firmagon injections.
I have not consented yet because I was told at the outset that they favored Firmagon because Lupron caused a short-term rise in testosterone. My concern is that Lupron might cause a flare up even though I taken 4 months of Firmagon injections.
Vegasman profile image
Vegasman
in Advanced Prostate Cancer
7 months ago

6 months in and ADT already failing

Firmagon and Zytiga. Was scheduled to have surgery, but that's off the table since its spread to lymph nodes in neck region. Starting chemo next week. Looking for stories of hope. How long do we have? To know its already MCRPC is devastating.
Firmagon and Zytiga. Was scheduled to have surgery, but that's off the table since its spread to lymph nodes in neck region. Starting chemo next week. Looking for stories of hope. How long do we have? To know its already MCRPC is devastating.
mysticmini profile image
mysticmini
in Advanced Prostate Cancer
5 months ago

Trelstar Mixject

When I looked it up on google, it stated it was for palliative treatment when Eligard and Firmagon fail. The Eligard seems to be working just fine. This confuses me because my PSA is still <0.01 as of September 2022. No Pain nor any known changes.
When I looked it up on google, it stated it was for palliative treatment when Eligard and Firmagon fail. The Eligard seems to be working just fine. This confuses me because my PSA is still <0.01 as of September 2022. No Pain nor any known changes.
280scout profile image
280scout
in Advanced Prostate Cancer
1 month ago

Flomax and PC

Was taking Flomax before being diagnosed with PC, Gleason 8 Had 45 radiation treatments, currently taking Zytiga and Prednisone daily and monthly injections of Firmagon. Question: Should I stop taking Flomax while being treated for PC? Thanks in advance.
Was taking Flomax before being diagnosed with PC, Gleason 8 Had 45 radiation treatments, currently taking Zytiga and Prednisone daily and monthly injections of Firmagon. Question: Should I stop taking Flomax while being treated for PC? Thanks in advance.
Vegasman profile image
Vegasman
in Advanced Prostate Cancer
6 months ago

Nothings worked. Help please

Started Firmagon injections. psa May 2022 1.42 started docetaxel in May too. After 6 cycles psa 8, moved directly onto Cabazitaxel, after 3 cycles psa 150. Started xtandi after 1 month psa down from 150 to 115, after second month, now, psa 210. Hubby comes out of hospital today after 9 weeks.
Started Firmagon injections. psa May 2022 1.42 started docetaxel in May too. After 6 cycles psa 8, moved directly onto Cabazitaxel, after 3 cycles psa 150. Started xtandi after 1 month psa down from 150 to 115, after second month, now, psa 210. Hubby comes out of hospital today after 9 weeks.
GinnyGinGin profile image
GinnyGinGin
in Advanced Prostate Cancer
1 month ago

Can i switch to Eligard from Firmagon ?

My real question is I will be traveling overseas in a few months and my onc told me they can do a 3 months Eligard shot instead of Firmagon so I can travel with no worry.Apparently they do it from buttocks.Has anybody switched from Firmagon to Eligard ?? Which one is less painful ?
My real question is I will be traveling overseas in a few months and my onc told me they can do a 3 months Eligard shot instead of Firmagon so I can travel with no worry.Apparently they do it from buttocks.Has anybody switched from Firmagon to Eligard ?? Which one is less painful ?
mynacho profile image
mynacho
in Advanced Prostate Cancer
6 months ago

Using transdermal E2

Has anyone switched from using Lupron (or any 1st or 2nd level ADT, such as Firmagon, abiraterone, etc.) directly to transdermal E2? 2. Has anyone who has used it eventually become castrate resistant, as with ADT? 3.
Has anyone switched from using Lupron (or any 1st or 2nd level ADT, such as Firmagon, abiraterone, etc.) directly to transdermal E2? 2. Has anyone who has used it eventually become castrate resistant, as with ADT? 3.
dhccpa profile image
dhccpa
in Advanced Prostate Cancer
5 months ago
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