My husband has been fighting Stage IV PCa for almost 4 years now. In this time he has gone through castration, 50 rounds of radiation (various areas), multiple chemotherapy (Taxotere, Xtandi, Radium 223, Jevtana and now back on Taxotere again. Except for the first round of Taxotere, when he was at his strongest, he has been unable to finish any one of these therapies due to intolerance or ineffectiveness against his cancer progression. For the past 3 months he has been hospitalized 3 times for pain control. He has been bedridden and hardly able to get back and forth from the bathroom due to weakness. He is currently on morphine and fentanyl patch for his pain control, zofran for his nausea from the morphine and of course the much needed laxatives from taking narcotics. His PSA continues to climb and his scans continue to show growth/progression of his disease. He is finding it more and more difficult to figure out "why" he's doing this and wonders when to stop the madness of it all. I realize this is a positive site for people, but with his Onco continuing to want to give him chemo that he can't tolerate, we don't know what to do or who to turn to. How do you admit to yourself that quality is more important than quantity?? I realize that the ones to answer this question are the ones who have made this decision, hoping to get some nuggets! God Bless.