I am 81 year old who has gone from being, supposedly, free of Pc in May 2016 to having Pc Gleason 3+4=7 in June and then Gleason 4+5=9 with metastases in August 2017.
In 2014 I had a DRE and Ultrasound of the bladder which were clear so went on medication (Flowmaxtra) to improve my peeing. I has PSAs regularly which were about 1.0 but but in May 2016 my peeing became more difficult and I was recommended to have a TURP.
In June I had the operation and a biopsy was carried out on the removed material. This came back G 3+4=7 but the PSA was only 1.03. A CT scan and Bone Scan showed that I had no metastases.
I was put on watchful waiting and had PSAs after 3 and 9 months which were both below 1.0. By now I had a lot of blood in my urine which was put down to my cycling and blood thinners. I complained to my urologist who said that a cystoscopy would put an end to my concerns.
The cystoscopy was interesting as the urethra was blocked by a bleeding mass of tissue. I was in exploratory surgery as soon as my blood thinners allowed.
On August 2 2017 biopsies were taken from the removed tissue to ease the blockage. The results were devastating. The were G 4+5=9 and a Bone Scan showed that I had metastases in my acetabulum, pelvic girdle and right ankle. The biopsy also showed a rare cancer was present in the sample.
From the European Society of Radiologists:
• 4.- PLEOMORPHIC GIANT-CELL ADENOCARCINOMA:
• This is an exceptionally rare variant of adenocarcinoma with giant pleomorphic
• Few cases have been reported. In the largest series, patients ranged in age
from 59 to 76 years.
• Gleason score 9 is usually seen in many cases of adenocarcinoma.
• The disease course is very aggressive
I sought a second opinion from a medical oncologist who agreed with my urologist that the only treatment was ADT and palliative radiation as required to ease pain from the metastases. He also advised that he would not recommend chemo due to age.
So now I am on Zoladex and suffering from extreme fatigue. My bike has not been ridden since last October but at least I didn't need am RP