I was dx in Feb, 2016 with advanced pca with a gleason score of 8 and PSA 8.8. My left seminal vesicle was invaded, along with 2 bone mets (femur and hip), and suspected pelvic nodal involvement with two nodes being affected (both approximately one centimeter each). I began treatment March with Casodex and a three month Lupron injection, and in August, replaced the Casodex with Abiraterone (1000 mg daily) to go with my three month Lupron injections. My PSA and Testosterone levels immediately dropped after my initial Lupron treatment and my PSA and testosterone have been undetectable since June 2016. Tumor analysis shows I have TP53 and TMPRSS 2 mutations. I found a surgeon who will do an RP in addition to my current ADT, and am wondering if anyone else with with stage 4, D2 PCA has either gone through this procedure, when standard of care just wants to treat with ADT, and possibly chemo? It seems, and I have read, that the oldest and concentrated cells are in the prostate and just by removing those, it could more effective in fighting this battle. I also forgot to mention that I would plan on having the lymph nodes removed, or radiated along with the bone mets as part of the program. I would so much appreciate any advice from anyone out there and I wish you all a Happy, and pca butt kicking new year!