Wanted to ask your advice regarding my PSA rise.
Background: Diagnosed 25-months ago, Stage 4 Metastatic PcA, Gleason 4+4=8, Bone mets in T8 vertebra and small spot in pelvis. Had radiation treatment in spine for pain, Lupron since diagnosis, 6 rounds of chemo (taxotere) that finished 18-months ago (Stampede).
My PSA at diagnosis was 227. The first month it dropped to 9.4 and dropped to 0.1 within 4-months. Stayed at 0.1 for about a year. Been rising slowly for 9 or so months, increasing about 0.1 each month. Leveled off for 3-months at 0.8. Jumped from last month to this month to 1.1.
When is a rise enough to raise concern that my cancer may have started to return? I'd greatly appreciate any insight you might have.