I an Dennis I have Stage 4 prostate with bone metastasis. Diagnosis in 2011

I was on vacation and had such server pain in my back, hips,neck and legs I was sure my arthritis was running amuck.  We went home and I went to my rumaoligest.  After a bone survey the next day I had a call from the rumaoligest to come in that day. When I got there he said I should see a oncologist. He said he thought I had bone mets probably from prostrate cancer. 

A couple months before I had a complete exam and had a PSA of 3.5. What a shock! I have never had an abnormal PSA. My oncologist said it is unusual but happens sometimes.  

My cancer is very aggressive a 9 out of 10. I am now on Xgeva, Lupron, prednisone  and zytiga. 

19 Replies

  • What a lovely paper.  Some indication of how much curcumin is needed would be useful, homecures.  I have been taking the stuff for years. I have had huge (as high as 70%) falls in PSA while taking such drugs as Lupron that I -- rightly or wrongly -- ascribe to help from the curcumin, the curcumin alone seems to have little inhibitory effect when I am not on the drugs. 

  • No problem: Goodhealth Naturally Curcumin x4000. 

  • You should not be using this forum to promote your worthless supplements.

    Show me 1 double blind study where curcumin has any effect against prostate cancer in humans

  • You say "curcumin cures all types of cancer"...wow...I guess you are way smarter than "all the dumb" guys here wasting their time with oncologists and drugs like firmagon, zytiga, xtandi, and xofigo...according to you all they need to do is pop curcumin caps...get lost you lousy scammer

  • Google throws up in excess of 30,000 responses to the query, but very few are to "Clinical Studies".

    Many of the query results are to suppliers of supplements, anecdotal reports and general discussion of herbs.

    That is not to say the results aren't worth looking at, but they are not "Clinical Studies" which implies a degree of independent evaluation.  

    There do appear to be some valid clinical studies and they do suggest some value in use of curcumin for cancer treatment, but let's not get carried away.  There are nothing like 30,000 studies.  

  • Homecures, you need to get with reality.  You claimed that there were " in excess of 30.000 clinical studies confirming the benefits of curcumin in the treatment of prostate cancer listed".  That is not correct.  In fact I would doubt that there have been anything like 30,000 clinical studies into prostate cancer regardless of the context.

    I did get in excess of 30,00 results (in fact 38,000) for a Google search of "curcumin prostate cancer ncbi", but only a very small number were clinical studies.

    And I am not denying the value of curcumin in the treatment of cancer, but lets get it into perspective.  There have been some studies which suggest it could be of value.  Accept that and move on, but to claim there have been 30,000 clinical studies devalues your credibility.

  • That's utter nonsense.  So-called "Alternative" practitioners and peddlers of all kinds of esoteric potions, nostrums and panaceas are not giving away their alleged treatments for free.  Staggering amounts of money are being made with practically no scientific rigor, regulation, oversight nor accountability whatsoever.  

    Worse still is that many are profiting by offering FALSE HOPE to desperately ill people- something that I find to be morally reprehensible.

     Anyone wishing to learn more is welcome to click on the link below for more information:


  • I am interested in hearing about your personal journey with Prostate Cancer.

  • I use curcumin, but there is something distateful about:

    "if you put "curcumin prostate cancer ncbi" in to Google, for example, you get in excess of 30.000 clinical studies confirming the benefits of curcumin in the treatment of prostate cancer listed"

    which is pure nonsense.

    ClinicalTrials.gov lists 4 PCa trials, 3 of which are still recruiting.  The only completed study used curcumin in conjunction with radiation.  Certainly not curcumin as monotherapy.


  • Homecures, you do really need to start learning about the relationship between an internet search term and the results thrown up.  They are NOT all directly relevant.  Instead of just looking at the numbers, have a look at some of the results and you will soon see that only a few relate to the very specific search phrase  The rest are only partially relevant and relate to just some of the terms in the search request. Go down a couple of pages of the results and you will soon see that not many include the NCBI part of your search.

  • Sorry for the news and I wish you the best of luck.  Even though it is a shock to have cancer, there is still a lot of reason for hope.  Be strong!  You have a lot of people pulling for you!

    It is unfortunate that many men (including myself up to last December) think that prostate cancer is the "good" cancer. That it is always slow growing and that you can always rely on the PSA test.  Unfortunately that is not always true.  

    My PSA #  low up to last December.  Then it went up to 4.3. A month later it was 11.  Today I am in day five of post surgery.  (I had to beg the Dr. to do the surgery as he thought it was already to advanced as it was also in lymph nodes.) The surgeon stated it is high risk cancer, at least T3N2 with G of 8,  and he expects the cancer to be upgraded when the pathology reports come back.  In any case, I will be starting radiation and hormonal theories once I have recovered from the operation and they get a new baseline PSA.  

    Your comments about arthitis pain hit home.  I have a lot of arthitis pain in my shoulders, neck, tailbone and knees.  Fortunately for me the bone scan was negative.  That all said, I am planing to be around for a long time (I am 58.)

  • Dennis,

    You are taking the good drugs to slow the spread of your PC.  I have taken them all and the Zytiga actually got my PC out of my lymph nodes.  My bone mets stabilized at six.  My stage IV diagnosis was in 2012.

    There are also three other drugs I take that are cheap and that do not add to the side effects of hormonal therapy for me.  Metformin helps suppress blood sugar surges that cause inflamation and immune suppression and has strong metadata analysis and clinical trials showing its effectiveness with PC.  

    Crestor is the one statin that you can safely use with Zytiga.  It suppresses LDL cholesterol (fat in your bloodstream).  Most people who fail HT like Zytiga have high LDL.  I am told LDL is prostate cancer's second food of choice if the androgen is suppressed.

    Avodart keeps testosterone from converting to androgen (dyhidrate testosterone) that is PC's first choice of food.  It completes the HT or androgen depravation therapy with Zytiga and Lupron.

    I would also recommend Xofigo for your bone met pain.  I completed this six month treatment a year ago. It will lessen bone met pain for sure, and has the possibility of healing some existing bone mets along with your other treatment. It healed three of my six bone mets completely, and perhaps more.  Bone mets disappear from scans slowly.  You take Xofigo  along with Lupron and Zytiga, but I think you would stop Xgeva to start Xofigo.  I did.

    A good Mediterranean diet with some supplements is also really important to make your body a very poor host to your cancer. The book "Anti-Cancer" explains this best. The book is also very inspirational.

    And exercise helps you retain a little muscle and quality of life. It is particularly important in keeping  your lymphatic system and liver up to the task of clearing out all the debris that cancer and drugs create.

    It is a helluva fight but you can win many precious years or more.  May your life be good and long.

    A brother in the fight,


  • Bob thanks for the answer and offering help. Two years ago I completed 9 months of xofigo treatments. It helped but not as much as I expected. I have kidney disease and non alcohol related liver disease.  I can't have C.T. scans with dye because of my kidney disease. I can't have a M.R.I. because of I have a pacemaker. I end up with a nuclear bone scan ane a skeletal survey xray to check the progress of the p.c. and bone mets. I have found that CBD does a great job helping ease my pain.  For me it works better than norco and lasts more than twice as long. It also eases chemo sickness. I am not an add for CBD it helps me but I can't say if it would help others. My cancer is progressing very slowly right now and I hope it stays that way or stops.


  • As do I, Dennis. Stay well my friend.


  • Zytiga did give me swelling in my feet, even with the accompanying prednisone.  In a month the pain stopped and the swelling went down.

    I use two supplements in addition to Metformin to help reduce inflamation.  They are nattokinase and Wobenzyme.  Maybe they helped.


  • WinnipesaukeeBob,  I have one question to interject, I have a lot of foot pain especially when I first awake and step out of bed. My feet feel hot and the bottoms of my feet seem swollen when I awake. I have had problems with Planter Fasciitis but it has disappeared. Do some of the Hormone Therapy drugs cause inflammation on the bottoms of your feet? My oncologist does not think so. You mentioned about Metformin for inflammation caused by blood sugar surges, could my pain be a start of neuropathy?

  • Docbulldog

    I think you have a reaction caused by one of your meds. After taking zytiga for several months I had my legs from the knee down and my feet would feel like I was stepping on hot coals. My oncologist didn't think that was the cause but the P.A.N. Rep said he has other patients with the same complaint. P.A.N. is the Patient Access Network they help me pay my share off the $9,000.00 a month the drug costs. The paln went away after a couple weeks and has not returned.


  • God speed!

  • Your story is a warning to us all. Take all pain seriously and seek out a consultant MD.

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