I was first diagnosed with Wegeners in November 2010 - sinus and lungs. Was on life support for 18 days. A small shadow appeared in 2015 in my lung and received 4 X 500 of rituximab and increased prednisolone (on 5mg maintenance) until all clear. I have all the usual other meds for diabetes etc. This May (2019) I was diagnosed with GPA again, this time in the kidneys. I was on cyclophosphamide tablets (150mg) for about 2 and a half weeks waiting for rituximab infusions - 2 X 500. Now on rituximab (500) 6 monthly for 2 years. Was on 15mg methotrexate weekly until this latest bout. I'm very suspicious that this relapse could have been caused by a Prolia injection - see this link
I would be interested if someone has also heard of this possibility.