Eosophils

[Madamec1]

Has anyone found a way of reducing Eosophil levels without Predisolone. Looking for a non drug alternative

[Hidden]

Do you have EGPA or is there some other reason for asking his question?

There are no evidence based non medication treatments for Vasculitis.

[PMRpro]

It all depends WHY the eosinophils are raised - they will fall if the cause is eliminated. But as Keyes says - there are no non-medication cures for vasculitis.

[ElaineRH]

Hi as I am aware there is no other non drug treatment for vasculitis. I have recently diagnosed EGPA. I have been on very high dose prednisilone since August and ever time I lowered the dose to less than 30mg the eosinophils rocketed. I was given Mepo (officially for my severe asthma) and the eosinophils dropped immediately to normal levels, although still not near to the 0.03 that the specialists would like its a step in the right direction. I have reduced my pred to 15mg. I don’t feel any better but the bloods are good. Little or no side effects on mepo for me and I can now sleep !

[Madamec1 in reply to ElaineRH]

Thank you Elaine. I will talk to my consultant tomorrow as the Pred makes me feel dreadful at times, sweats, shaking and not being able to think straight . I think walking everyday is doing me good though

[Vo321 in reply to Madamec1]

I was initially on 50mg Pred and now on 20mg. I agree, when I was first put on Prednisolone I was sure I was going out of my mind. Shaking, random anger, hunger, insomnia etc. but as I've lowered the dose I found these symptoms to improve.

[Madamec1 in reply to Vo321]

Now down to 9mg on Aza, Urso & Alendronic. Taking care what I eat and getting plenty of exercise/gym, walking. Mind is clearer and I feel a lot healthier now. Way forward 🏋️‍♀️

[Madamec1 in reply to Madamec1]

I have also a nutritionist and allergy specialist at my local health food store. So although I don't have any specific allergies I am sensitive to whole grains,honey, soy, malt vinegar & mono sodium glutamate, uncooked apples. I don't put milk in tea or coffee but have Almond milk/coconut milk in smoothies, puddings. Both have a good taste

[ElaineRH in reply to Madamec1]

I was just reviewing my older comments and thought you might like an update- I eventually came off Mepo as my lung function fell dramatically . I tried azathioprine for some months but had a recurrence of the Pulmonary infiltrates.

I then had another drug called Reslizumab which I had an anaphylaxis episode so stopped after 10 mins.

The 40-50 mg of Pred dint control the eos very well so was give 80mg IM triamcinolone every six weeks. I really didn't cope at all - mentally very unstable, lost weight, didn't sleep at all ....

Now on Benralizumab and 5 mg only of Pred for Adrenal insufficiency . Eosinophils are around zero. My consultant feels that the new biologics prefer better than the chemo type which wipe out all of the white cells rather than target the one that causes an issue. I don't feel massively better but suspect that that's to be expected. They are looking to tweak some other things to see if there can be any physical improvement .

How are you doing

BW

Elaine

[JennH2022]

Start by getting tested for allergies (I recommend a blood panel instead of a skin test)

All pollen allergies correlate with foods. They won't register as true food allergies, but you can find plenty of information on "pollen food allergies".

If you have more than one pollen allergy, the food list can be really long.

Eliminate those foods altogether and see you feel.

My EoE has been reduced to "mild" and is only detectable pathologically now. I have a very limited diet of fresh produce. I also recommend you join a support group (some are available on FB).