Recent test results

[Colvic]

Hi, have been trying to sort out my health for the last 10 years. Have been put on b12 tablets, vitamin D, B complex and levothyroxine 150mg. I have extreme brain fog/spaced out feeling, weak legs, night sweats. My blood sugar also drops. My free T4 has always been high and my TSH has been at 0.02 a year ago, I was told to lower my dose to 150 from 175. I am now being told to increase it again, I just feel like I'm going around in circles. Any ideas?My most recent results are

TSH 6.7 (0.2-4.0)

Free T4 21.6 pmol /L (10-22)

Vit D 62 nmol/L (>50)

B12 502 Ng/L (150-1000)

Serum folate 11.2 ug/L (2-18)

Ferritin 251 ug/L (12-250)

[FallingInReverse]

Any luck getting a FT3 result?

Your tsh is too high, but your FT4 is also. Chances are you gave low FT3 causing at least some of your issues.

Also - in a past post, your iron/transferrin saturation percent were too high. You’re not supplementing iton, are you?

Also since you had very very high CRP last time (do you know why?), you should make a habit of always getting CRP tested with your ferritin. High CRP will increase your ferritin result but it’s due to inflammation nut true iron status.

B12 and folate are ok, but should he higher - folate top of range and b12 targeting minimum 500 but could go top of range for that too.

Lastly - in general, our bodies don’t like whiplash/zigzags when it comes to hormones. Your doctor obviously doesn’t quite know how to treat thyroid issues, but replies in your last post and soon this one will help you see the bigger picture.

[TiggerMe Ambassador]

I agree with FiR, these results suggest you aren't converting enough to fT3, also your Vit D is too low aiming for 125nmol/l

grassrootshealth.net/projec...

[Colvic in reply to TiggerMe]

Thanks for you response. The lab suggested PA or coeliac, I was tested for PA and told it was negative, they are going to test me for coeliac. They didn't do a FT3 this time. The only other test result that was noted out of range was serum alanine animotransferase 62 ul (0-40). No mention of iron this time. I don't supplement iron. What is CRP? The doctors told me I need to increase my levo again which I don't want to do.

[TiggerMe Ambassador in reply to Colvic]

Have you ever had a fT3 result? Any idea how well you convert?

The serum alanine aminotransferase (ALT) result shows that your liver isn't happy which isn't unusual for Hypos

CRP is a general inflammation marker

Your Dr is a fool as above range fT4 is not good for your health! You are right in refusing an increase

You need to request a referral to Endocrinology, take a look at the list as you can request a named Endo in your area so worth aiming for one with T3 knowledge...

thyroiduk.org/contact-us/ge...

[Colvic in reply to TiggerMe]

The last FT3 results I had was 5.5 pmol and 6.2 pmol (3-6.8) I requested a referral to endo but the last time I was there they told me it wasn't my thyroid to blame.

[TiggerMe Ambassador in reply to Colvic]

What were your other levels with those results?

Do you test early morning, fasted 24 hours after last dose?

What does he say to explain the raised TSH?

[Colvic in reply to TiggerMe]

My ft4 was 24.3pmol (10-22)Tsh 0.43 mlul(0.3-4.5)

This was back in February 2023.

I always test before 10am and I don't take my levo until after the test.

[TiggerMe Ambassador in reply to Colvic]

Did you feel any better on 175mcg?

Night sweats can be due to low testosterone have you had that checked?

Also low B12 can be the cause

[Colvic in reply to TiggerMe]

About 4 years ago they said I had low testosterone, I had a repeat blood test and it came back borderline so they said I was fine. I have had the same symptoms for 10 years, when I found out my b12 and D was low I thought I'd finally found the answer but nothings made any difference yet. My wobbly legs are at the worst they have ever been and my ability to do more than one thing at a time is terrible now.

[TiggerMe Ambassador in reply to Colvic]

I would certainly request a trial of testosterone as I've certainly found it a great help with muscle strength and general resilience (and I'm a girl!)

[Colvic in reply to TiggerMe]

Interesting, I will do that.

[TiggerMe Ambassador in reply to TiggerMe]

Reading between the lines of these results it suggests your pituitary likes the higher level of fT3 which presumably dropped when lowered to 150mcg which keeps your fT4 within range but likely drops your fT3 too low

If you improve your Vit D, B12 and folate levels this will help to get the best conversion, do you also take a good B complex which could help with the brain fog

[TiggerMe Ambassador in reply to TiggerMe]

I'm diving out for a few hours

TBC 🤗

[Colvic in reply to TiggerMe]

I take igennus super B complex one a day although it does say to take two. I also take igennus D 2000iu per day and 50mcg of b12 per day.

[TiggerMe Ambassador in reply to Colvic]

So currently taking 500mcg B12 combined, looks like taking the 2nd Igennus would be a good idea to help with B12 and folate levels

Igennus D lacks K2 MK7 and is a low dose (Vit D good for bones but needs K2 to get the calcium to them rather than clogging up blood vessels)

I'd suggest adding another Vit D (until you've used them up) which contains K2 like Nature Provides sublingual which is easier to alter the dosing... you need to up your dose, if you put your details into this calculator is will show you the options... grassrootshealth.net/projec...

Aiming for 125nmol/L I'd suggest a loading dose and then drop back to a maintenance dose which is often 4-5,000iu

[Colvic in reply to TiggerMe]

Thank you for your help. I will start taking more vitamins tomorrow and see how it goes while I'm waiting to go to the endo.

[Sparklingsunshine in reply to Colvic]

A negative PA text doesnt mean you dont have it, merely there arent enough antibodies to show up at the time. Antibodies fluctuate. And its a notoriously unreliable test.