b12 high : hi all. has anyone ever had high b1... - Thyroid UK

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b12 high

CAB123x profile image
22 Replies

hi all.

has anyone ever had high b12?

I read somewhere that high b12 results actually meant there was a deficiency (make it make sense lol)

Anyone have any ideas? X

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CAB123x
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22 Replies
greygoose profile image
greygoose

How high is high? Can you give us the actual numbers, please? The ranges are of little use where B12 is concerned.

Have you had your folate tested? B12 can be high due to low folate, because the two work together.

jgelliss profile image
jgelliss in reply togreygoose

GG thank you for this information . Glad to learn . This forum is chuck full of very valuable information. Thank you for your Great contributions.

CAB123x profile image
CAB123x in reply togreygoose

It wasn’t overly high the range was (187-883) and mine was 930.

Folate was (3.1-20.5) and mine was 8

greygoose profile image
greygoose in reply toCAB123x

Even though it's over-range, that is not excessively high for B12. It's the range that is the problem - and at best, ranges are only a rough guide. So, given that you are taking B12 (a multi-vit?) and that your folate is low, it's not surprising that your B12 is that high.

What you need to do is raise your folate.

CAB123x profile image
CAB123x in reply togreygoose

How do we raise the folate? X

greygoose profile image
greygoose in reply toCAB123x

By taking it.

But I can't suggest anything without knowing what you're already taking.

CAB123x profile image
CAB123x in reply togreygoose

I only take iron supplements and vitamin D (stopped taking b complex vitamin when the high b12 came back)

greygoose profile image
greygoose in reply toCAB123x

OK, so If I were you, I'd get some methylfolate tablets, about 400 mcg, and take those until the pot is empty. then go back on your B complex as a maintenance dose. The B12 will probably drop as the folate increases.

Are you taking vit C with your iron, and magnesium and vit K2-MK7 with your vit D?

CAB123x profile image
CAB123x in reply togreygoose

is this one ok x

Folate
greygoose profile image
greygoose in reply toCAB123x

That one is fine. :)

CAB123x profile image
CAB123x in reply togreygoose

What type of magnesium would you recommend?? There seems to be a few out there x

greygoose profile image
greygoose in reply toCAB123x

It depends what you want it to do:

healthunlocked.com/thyroidu...

helvella profile image
helvellaAdministrator

Are you taking any B12?

There can be some concern if your B12 is very high despite NOT taking any B12 supplements.

CAB123x profile image
CAB123x in reply tohelvella

It wasn’t overly high the range was (187-883) and mine was 930.

Folate was (3.1-20.5) and mine was 8. I’ve been taking a supplement with b12 in so maybe that’s why x

helvella profile image
helvellaAdministrator in reply toCAB123x

It seems to me the likeliest explanation.

KateJS profile image
KateJS

yes! I have high B12 and heard the same thing. Mine should be depleted too as I take Metformin. My private Thyroid Dr also suggested that I supplement with B12 as I may not be absorbing properly which is why it’s floating around in my blood… I’ve only been taking it a few days so too early to tell if it’s making a difference or not but it supposed to help with tingling and nerve issues

CAB123x profile image
CAB123x in reply toKateJS

I made the mistake of googling high b12 and now convinced myself I’ve got something terrible! It wasn’t overly high the range was (187-883) and mine was 930.

Folate was (3.1-20.5) and mine was 8

Xx

Poniesrfun profile image
Poniesrfun

it’s a genetic thing that prevents utilization and elimination of B12. So you may have elevated B12 in your blood but a cellular deficiency. If that is not the case for you and you are not supplementing B12 or B complex, a very high B12 can be an indicator of colon cancer. My B12 was more than double the upper range. I did have a tumor and after colon surgery B12 quickly dropped to mid range almost immediately.

Patti in AZ

CAB123x profile image
CAB123x in reply toPoniesrfun

Thank you for this. Do you have any idea how we can test to find out if it’s a cellular deficiency? X

humanbean profile image
humanbean

I almost always have high B12 (over the range). My serum level has been as high as

> 2000 ng/L but it does drop when I reduce or stop supplementing. My Active B12 is usually over the range too and drops when I reduce or stop supplementing.

I take a B Complex with occasional high dose Methylcobalamin. Some links you might find reassuring :

Choosing a B12 supplement :

perniciousanemia.org/b12/fo...

Optimal levels for B12 :

perniciousanemia.org/b12/le...

perniciousanemia.org/b12/le...

And a couple of interesting articles :

stichtingb12tekort.nl/engli...

stichtingb12tekort.nl/engli...

There are possible reasons why B12 being high without supplementing might be a concern :

researchgate.net/publicatio...

CAB123x profile image
CAB123x in reply tohumanbean

So informative and reassuring thank you!! X

Poniesrfun profile image
Poniesrfun in reply toCAB123x

The pernicious anemia site contains the same references I would have suggested (thank you @humanbean). If you have a serious condition related to excessively high B12, you’ll likely also have symptoms and/or it will show up in other blood work (CBC, liver, kidney labs, colon screening, etc.)

Patti in AZ

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