newcomer questions: hello! I’m just after some... - Thyroid UK

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newcomer questions

PlatypusProfit8077 profile image

hello!

I’m just after some info about thyroid levels.

I don’t know much about it and I’d like to know if it’s contributing to me feeling lousy. 36yo female, Australia

TSH 1.15 mIu/L (range 0.4-3.5)

Free T4 10.9 pmol/l (range 9.0-19.0)

I have B12 deficiency, Raynauds, and recent tests showed mild deficiency in Vit D (44nmol/l from a range of 50-140). I’ve heard the words mild deficiency before with the B12 though so I’m assuming it’s actually not great.

thank you!

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4 Replies
SlowDragon profile image
SlowDragonAdministrator

Ft4 is very low in range

TSH is not responding to that

Improving low vitamin levels is first step

Then retest thyroid including thyroid antibodies and Ft3

Also request ultrasound scan of thyroid

You need folate and ferritin levels tested too

Ideally full iron panel test as well

Are you vegetarian or vegan

Any autoimmune diseases in your family

For full Thyroid evaluation you need TSH, FT4 and FT3 tested

Also both TPO and TG thyroid antibodies tested at least once to see if your hypothyroidism is autoimmune

Very important to test vitamin D, folate, ferritin and B12 at least once year minimum

Low vitamin levels are extremely common when hypothyroid, especially with autoimmune thyroid disease

About 90% of primary hypothyroidism is autoimmune thyroid disease, usually diagnosed by high TPO and/or high TG thyroid antibodies

Autoimmune thyroid disease with goitre is Hashimoto’s

Autoimmune thyroid disease without goitre is Ord’s thyroiditis.

Both are autoimmune and generally called Hashimoto’s.

Significant minority of Hashimoto’s patients only have high TG antibodies (thyroglobulin)

Often medics only test TG antibodies if TPO are high

20% of autoimmune thyroid patients never have high thyroid antibodies and ultrasound scan of thyroid can get diagnosis

In U.K. medics hardly ever refer to autoimmune thyroid disease as Hashimoto’s (or Ord’s thyroiditis)

For good conversion of Ft4 (levothyroxine) to Ft3 (active hormone) we must maintain GOOD vitamin levels

VERY important to test TSH, Ft4 and Ft3 together

Recommended that all thyroid blood tests early morning, ideally just before 9am, only drink water between waking and test

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)

PlatypusProfit8077 profile image
PlatypusProfit8077 in reply toSlowDragon

thank you!

You need folate and ferritin levels tested too

- folate was 56 something (I take a small dose on injection days plus my diet has lots of folate rich foods)

- ferritin was 53 (sorry don’t have my tests with me right now)

Ideally full iron panel test as well - my levels were good last test, including the ferritin of 53. I think that’s the highest I’ve ever had in my life.

Are you vegetarian or vegan - no, very balanced diet

Any autoimmune diseases in your family - pernicious anaemia is under investigation. Mum has lupus and MGUS

For full Thyroid evaluation you need TSH, FT4 and FT3 tested - i think FT3 isn’t commonly tested or it’s a cascade test here in Australia, and since mine are in range, it hasn’t triggered the cascade? (Could be wrong)

Very important to test vitamin D, folate, ferritin and B12 at least once year minimum

- B12 injections frequently so testing is pointless

SlowDragon profile image
SlowDragonAdministrator in reply toPlatypusProfit8077

Your mum has autoimmune disease

Request that both TPO and TG thyroid antibodies are tested at next test

As you have B12 injections it’s recommended also to supplement a good quality daily vitamin B complex, one with folate in (not folic acid) may be beneficial.

This can help keep all B vitamins in balance and may help maintain B12 levels between injections

IMPORTANT......If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 5-7 days before ALL BLOOD TESTS , as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

In week before blood test, when you stop vitamin B complex, you might want to consider taking a separate folate supplement (eg Jarrow methyl folate 400mcg)

Post discussing how biotin can affect test results

healthunlocked.com/thyroidu...

helvella.blogspot.com/p/hel...

SlowDragon profile image
SlowDragonAdministrator

Vitamin D need improvement to at least around 80nmol

GP will often only prescribe to bring vitamin D levels to 50nmol.

Some will prescribe to bring levels to 75nmol or even 80nmol

leedsformulary.nhs.uk/docs/...

GP should advise on self supplementing if over 50nmol, but under 75nmol (but they rarely do)

mm.wirral.nhs.uk/document_u...

But with Hashimoto’s, improving to around 80nmol or 100nmol by self supplementing may be better

pubmed.ncbi.nlm.nih.gov/218...

vitamindsociety.org/pdf/Vit...

Once you Improve level, very likely you will need on going maintenance dose to keep it there.

Test twice yearly when supplementing

Vitamin D mouth spray by Better You is very effective as it avoids poor gut function.

There’s a version made that also contains vitamin K2 Mk7.

One spray = 1000iu

amazon.co.uk/BetterYou-Dlux...

It’s trial and error what dose we need, with thyroid issues we frequently need higher dose than average

Vitamin D may prevent Autoimmune disease

newscientist.com/article/23...

Web links about taking important cofactors - magnesium and Vit K2-MK7

Magnesium best taken in the afternoon or evening, but must be four hours away from levothyroxine

betterbones.com/bone-nutrit...

medicalnewstoday.com/articl...

livescience.com/61866-magne...

sciencedaily.com/releases/2...

Recipe ideas

bbc.co.uk/food/articles/mag...

Interesting article by Dr Malcolm Kendrick on magnesium

drmalcolmkendrick.org/categ...

Vitamin K2 mk7

betterbones.com/bone-nutrit...

healthline.com/nutrition/vi...

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