Is this poor conversion? : Hi all, it's been a... - Thyroid UK

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Is this poor conversion?

Eoperez profile image
8 Replies

Hi all, it's been a while since I posted. My thyroid results are just in and these are the results and GP want to speak to me. They were done 1st thing in morning before food and didn't take my 175mg of Levothyroxine that morning. TSH has been 0.05 for years.

I think I'm not converting T3 properly now, is this correct? If so, what are the options?

Also, on a side note, I've been seeing a Menopause GP for HRT. She decided to look through my medications and has stopped my folic acid as apparently I won't be anaemic anymore as I've had a hysterectomy. I tried telling her it was B12 deficiency but as I self inject it has fallen off their system that I have had low B12, folate & ferritin. I've tried to get my usual GP to add it back but they've said I need my folate retesting. They were supposed to do this along with my thyroid tests but I'm not sure they did.

Thanks

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Eoperez profile image
Eoperez
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8 Replies
TiggerMe profile image
TiggerMeAmbassador

So you GP is going to want to lower your dose of T4 as you are above range and this can actually worsen conversion.... you are converting pretty well at the moment and a slight reduction would be a good thing as above range fT4 is not good long term, don't agree to more than a 25mcg drop

Free T4 (fT4) 25 pmol/L (9 - 23) 114.3%

Free T3 (fT3) 6 pmol/L (3.5 - 6.5) 83.3%

T4:T3 Ratio 4.167 

Surely whether you've had a hysterectomy or not they should be looking at your levels and going from there? Put your results up when you get them

Eoperez profile image
Eoperez in reply toTiggerMe

Thanks. I will. I'm thinking that a 25mcg drop per day is going to be too much, I've done this in the past and sharp felt rotten again. Do you think 25mcg/week would be sufficient to get t4 back down a little?

TiggerMe profile image
TiggerMeAmbassador in reply toEoperez

Doubtful but hard to guess, how about alternating 150/175 or even better if you have 25mcg pills you can cut in half to give you 162.5, not unusual to feel grim at some point within the first 6-8 weeks as things adjust and then perk up

Buddy195 profile image
Buddy195Administrator

I like to make slow and steady changes to medication. I would use a pill cutter and reduce Levothyroxine by 12.5mcg daily initially (or take 150mcg/ 175mcg alternate days). I certainly wouldn’t want over range FT4- it may be that you need to reduce by 25mcg over time. Remember to test levels 6-8 weeks after being on a new dose. I personally find it’s best to wait the full 8 weeks, as it takes me this long to fully settle on a new dose.

SlowDragon profile image
SlowDragonAdministrator

I would only reduce levothyroxine by maximum of 50mcg per week

Personally I would initially reduce by 25mcg per week

Wait 6-8 weeks t before either reducing again or retesting thyroid and vitamin levels first

As you do B12 injections it’s recommended also to supplement a good quality daily vitamin B complex, one with folate in (not folic acid)

This can help keep all B vitamins in balance

so start on a daily vitamin B complex

B vitamins best taken after breakfast

Igennus B complex popular option. Nice small tablets. Most people only find they need one per day. But a few people find it’s not high enough dose and you may find you need a separate methyl folate couple times a week

Post discussing different B complex

healthunlocked.com/thyroidu...

Thorne Basic B recommended vitamin B complex that contains folate, but they are large capsules. (You can tip powder out if can’t swallow capsule) Thorne can be difficult to find at reasonable price, should be around £20-£25. iherb.com often have in stock. Or try ebay

IMPORTANT......If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 5-7 days before ALL BLOOD TESTS , as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

In week before blood test, when you stop vitamin B complex, you might want to consider taking a separate folate supplement (eg Jarrow methyl folate 400mcg)

Post discussing how biotin can affect test results

healthunlocked.com/thyroidu...

helvella.blogspot.com/p/hel...

Eoperez profile image
Eoperez in reply toSlowDragon

Thank you, that was my 1st thought to reduce a little once per week. I'll have a read of the articles too. Thanks again

SlowDragon profile image
SlowDragonAdministrator in reply toEoperez

I would cut a 25mcg tablet in half and take 162.5mcg twice a week, and not on consecutive days

When you retest …..last dose 24 hours before test …..and perhaps make sure the last dose is 162.5mcg before test

angela100 profile image
angela100

Hi, I'm sorry that you are struggling, it looks like you're doing the GP's job for them. I've tried for years to get help from my GP, but gave up eventually. I now see a specialist privately, which is not cheap but worth every penny. Since being under his care, it has changed my life, I feel totally normal again and I am living my life to the full.

If you want more information, please send me a message privately. Sending love.

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