genetic tests for conversion issues etc

[Starseed56]

hi lovely forum users

I’ve finally got an endo appointment via my doctor no date yet. I doubt they’ll smile on my taking ERFA but I’ve no intention of going back to Levo only as it worked less and less for me over the years. I’ve wondered if I have a T4 to T3 conversion issue and have found a blue horizon test for this (regenerus have stopped theirs) this is what the test covers

bluehorizonbloodtests.co.uk...

I’m wondering if it’s a good idea to do this test now and have the results to hand when I go for my appointment as if I am a poor converter or have any of the other things the test covers it may be useful to have with me and help my case. it costs £145 so not to be under taken lightly! I’ve not been under an nhs endo for many many years. I’m thinking of using the medical negligence phrase as a last resort if they won’t/can’t prescribe NDT for me, but don’t want to go in all guns blazing! I’ve learned so much here about other optimum levels so I will try and get some help/understanding with my ferritin level too if I can. As yet I’m not sure my thyroid levels are optimum I intend to test by the end of the month so 2 months after I upped the dose to 2 grains a day.

Thoughts re taking the test prior to appointment? I’m guessing nhs wouldn’t do these tests?!

Thanks 🙏💜

[J972]

Hello,

I’ve been thinking about genetic testing myself recently but the cost of testing is off-putting. I thought there was a decent discount code (30%) available via TUK for the Blue Horizon test but I can’t seem to find it……perhaps it’s no longer available?

With regards to whether a positive result would be helpful from an NHS treatment point of view, I found this relatively recent thread:

healthunlocked.com/thyroidu...

[Starseed56 in reply to J972]

Hi J972 thanks for your reply. If you register with Blue Horizon you get a 15% off code which lasts for seven days.

You can get 10% off with TUK. I think I’ll go for it…thanks for your encouragement I’ll think positive that it can help me! 💜

[J972 in reply to Starseed56]

Oh that’s good to know! Good luck with it 😊

[samaja]

It all depends how likely your doctor is to take this into account in the first place because you could take the test and they dismiss it or it can get you the right medication at last if they listen. The next consideration, if they listen, is if they will require to see the test from a lab or would they believe your word. I didn't take the test but used the raw DNA data from my Ancestry UK test to find the relevant SNPs and did the DIY reading on the basis of Paul Robinson's blog which was enough for my private endo though by that point he knew that I research stuff and generally know what I am talking about. The Ancestry test is cheaper by more than half of the BH price. I know BH has more tests and markers but I sincerely doubt your doctor will have much idea what to do with most of the results.

And poor conversion is generally confirmed by you FT4 to FT3 ration when you are on no meds or on T4 only. You might have high RT3 but most doctors don't even know what this is.

[Starseed56 in reply to samaja]

Thanks for your reply, I’ve ordered the BH test so will see what happens, with results and when I see the endo. My FT4 was pretty high and my FT3 just scraped in to the “normal” range by 0.2 when just on Levo before I switched to ERFA, so am thinking I may be a poor convertor am praying the test backs this up and possibly some of the other markers too 🙏. I’m not sure I understand about RT3 either! 💜

[Auders]

I did the Regenerus test early last year. I took a copy when I saw my GP and she asked what it meant!😂 (got one dodgy Dio2 gene) I just did a quick explanation and she said “Oh, that’s interesting!” 😂 bless her