Menopause Hot Flush Medication Gets Approval

[Sparklingsunshine]

Another article from the Guardian regarding an alternative to HRT for those suffering from hot flushes during menopause. However it looks like its only going to be available privately for now. theguardian.com/society/202...

[TiggerMe]

Regenallotment

I think I remember seeing a programme a few years ago about a trial, the one lady that stuck in my memory suffered from hot flushes every few minutes and it changed her life... she was bereft when the trial ended and she had no further access to it 😩

[Regenallotment in reply to TiggerMe]

My wonderful DiL read this out to me this evening. She’s a nurse. We both spontaneously announced… what the hell is in that? Not touching it with a barge pole.

Hot flushes (Myhill/Williams)are commonly linked the high blood glucose. Stop the alcohol, stop the sugars/flatten your curve (Zoe/Wentz) and they go away. Prosecco is not your friend 🥂🚫 Switch to spirits if you have to, no sweeteners or ‘light’ mixers either. 🚫 Trip CBD drink is a nice alternative. Optimal thyroid hormones reduces nightsweats. HRT if you want it can do the rest. It’s the urtogestan rather than the oestrogen that does that for me. 🌱

[TiggerMe in reply to Regenallotment]

🤣 I caught a bit about it on the news, what were the side effects insomnia and nausea? Brilliant 😟

Like you say at least with hormones they are something the body is used too

[Buddy195 Administrator]

It’s good that Veoza is seen as an alternative to HRT ( in helping with hot flushes)for those women unable to take hormone replacement. However, the current cost of the treatment is very steep (& only available to under 65s)

In the US, the cost was set at $550 (£430) for a 30-day supply.

[Sparklingsunshine in reply to Buddy195]

I think the pharmaceutical company are seeking NICE approval so it can be available on NHS. There are many women who can't or who don't want to take HRT. They need a viable alternative.

[Buddy195 Administrator]

Absolutely. Hope it is available on NHS asap. 👍

[RedApple Administrator]

' it has not been studied for safety and efficacy in women over the age of 65, the MHRA said, so no dose recommendation can yet be made for this age group.'

Presumably no-one over 65 can possibly have menopausal hot flushes. At 59 years and 11 months you're eligible for the treatement, but on your 65th birthday the symptoms magically disappear!

#️⃣OneSizeFitsAll approach 😡

[helvella Administrator Thyroid UK]

"Veoza acts directly on the temperature control pathway..."

Which led me to wonder if it in any way interferes with thyroid - the hormones or their action or anything else. I did a quick search but found nothing relevant - neither positive nor negative - and only five uses of the word "thyroid" at all in published papers about fezolinetant/Veoza.

[TaraJR]

The age range is a concern, as already said by RedApple Though they may (hopefully) still prescribe for over 65s - its just that they don't yet have advice on dosing.

But at over £400 a month, I doubt ICBs will want to allow it anyway. I for one am gutted at the suggested price. T3 is now down at £42 and they still argue about that.