Have I cracked it?

[Regenallotment]

I'm not showing off here, there are a few of us members scratching their heads after having symptoms and signs of over replacement after careful titration and focus on gut health, adrenals, sex hormones etc, just sharing so we can all compare notes. Being over range came as a complete surprise and out of the blue.

So after my little over range debacle in June and July, I was titrating down down to get back in range which I managed end of Aug. I posted at the time and had dropped the Roseway T3 to zero for a few weeks because I was still getting palpitations.

Roll forward 6 weeks and palpitations have stopped, energy levels stable, aches receding. Eyes aren't great but specsavers checked and all OK typical for age, just needed a stronger script for reading glasses and better eyedrops, menopausal symptoms improving with some TLC and support from our dear old donkey friend  TiggerMe and heart rate lower since starting Adrenal Supplement from Pure encapsulations (no I didn't test, I'm broke, I went on symptoms, bought one that is fairly gentle). Also via Zoe programme and continuous blood glucose testing for 2 weeks and monitoring my diet in their app, found that my palpitations and sweats are linked to poor blood sugar control and not necessarily the Levo/Lio dose, so thats nice to discover. HRV is up again nearer 70 so I am pleased about that and night-sweats have gone thank goodness, I am loving the cooler air.

Is this the sweet spot; 75mcg T4 2.5mcg T3

Bloods taken after 24 hours of both. Not a chance in hell of me splitting a capsule smaller than 'about half' for the old 8 hours before routine. All other usual protocols followed.

TSH 0.01 (0.27-4.2)

FT4 21.3 (12-22)

FT3 6 (3.1-6.8)

TPO down a bit (still higher than at diagnosis) at 232 suggests that if it was a Hashi Flare and not just sudden absorption improvement it might be passing.

GP also tested recently and squeaked at the TSH, I explained the private prescription of tiny T3 dose and summer surprises and bless her she said .. thats fine then, well done, you really know how to look after yourself, I am pleased that all worked for you, I won't interfere. Halleluja 🙏

 helvella I started using your suggested technique dropping half-ish contents of a 5mcg capsule into a couple of tablespoons of water, it works a treat, I put the capsule back together and take the other half the next day. Weird though the Roseway Lio is BRIGHT blue - like turquoise/WKD alcopop slush puppy blue 😂

Thanks everyone who has chipped in, I'm sure there will be more adjustments at some point but I feel I can actually stick here for a bit and see how I go. 🌱

[helvella Administrator]

Positive improvements are always massively welcome as news and information - and very good to read.

[TiggerMe Ambassador]

Fabulous news! 🤗 Excellent lesson in tweaking, juggling, holistic mindfulness (is that even a thing?) and an understanding GP!!!!! Freaky 😵

Ride that wave 🏄‍♀️

[Delgor in reply to TiggerMe]

Absolutely fantastic news Reggie! Such an inspiration to everyone! Dare I say I always knew you could do it! Your hard work has certainly paid off! Feel so happy for you😁

[Lalatoot]

That's brilliant.

[Delgor]

Oops - trust me to make an ass of myself and replied to our lovely Donkey instead of you🤣

[Regenallotment Ambassador in reply to Delgor]

Lol that’s the sort of thing I would do 🤣 Thanks lovely hope you are doing okay 🌱

[radd]

Regen,

Amazing 👏👍 and I'm loving that you understand/consider the hows and why's, and have found yourself some answers. Being confident has a massive influence on the end result.

[ClareP5]

Great news - what a fab response from your GP.

[Ajva]

glad you have found a good balance. I am 4 years on still messing around with doses. I use the same place as you to source my medication and I used to be on the bright blue capsules. I kept getting really bad histamine reactions. But I am glad you are getting on with them.

[Regenallotment Ambassador in reply to Ajva]

Ah interesting, I’ll ask her next time, my eyes puff up at the slightest thing. What alternative did you go with? 🌱

[Ajva in reply to Regenallotment]

Yes my eyes were so itchy and I couldn’t smell or taste a thing for 8 months, thought it was just sinus problems as have had two surgeries in the past 2 years. But when I went back on NDT is calmed down.

I am now on mix of NDT armour and tirosint (which is a Levo brand) that roseways stock.

I would stick with your doses and meds if they are working for you. Everyone’s different!

[Hidden]

The ‘old eight hours before routine’ (actually I always make it 10 - 12 hours) is really the only of getting a fairly accurate FT3 reading. Arguably it doesn’t matter if you use the same protocol every time - but with FT3 at 6 after 24 hours I’d say that you’re moving towards overmedication.

The main thing is that you’re feeling better. I hope it continues.

[Regenallotment Ambassador in reply to Hidden]

Yeah I thought the same, the advice from Roseway is not to focus too much on the numbers now I’m close. I’ll keep an eye on symptoms and monitor regularly, thanks for saying though it’s great to have member scrutiny as it makes us think 🤗🌱

[Hidden in reply to Regenallotment]

I had the same view as you and found that my FT3 had risen from 6 - 7. Just that small rise made a massive difference and explained why I felt so ‘hyper’.

Don’t obsess about numbers but don’t ignore them. Keep an eye on everything 😉

[janeroar]

I think this is very inspiring and hopeful to read. Thank you.

[Baggiesfan]

Brilliant news, I wish my NHS consultant was more understanding, though to be fair she did phone me last week after I emailed her. My tsh is 0.05 and though my T3 and T4 are half way and below, (can't remember which is which at the moment) she refuses to endorse a small increase in either levo or liothyronine (75mcg and 10mcg). Says low tsh, below 0.1 causes heart and bone problems, then adds there's lots of research but I can't find it. Anyway congratulations on feeling better, so pleased for you, I'll put my own post on when I get results in writing.

[TiggerMe Ambassador in reply to Baggiesfan]

It'll be interesting to see your results as previously it looked like an increase in levo was going to be the better route for you ( you seemed to be a good converter), rather than muddying the results with T3 which looks like it has left you low in both... so same results when you were undermedicated on T4 alone but low TSH means a fight for any increase 😕

[Baggiesfan in reply to TiggerMe]

Thanks Eeyore, I'm still awaiting results in any form. I thought I was a poor converter but definitely improved when levo was upped to 75mcg a day from 50 with 10mcg lio. Prior to any lio ever and on 100mcg 5 days a week, 75 the other 2 days my tsh was 0.4 (0.27-4.2) 3.31%, T3 3.67(3.1-6.8)15.41%, T4 15.4(12-22)34%. Then after stopping lio due to ectopic heartbeats for 10 months, still had them so it isn't the lio, my tsh was 0.15(0.4-4.9)-5.6%. Either way I'll post results when I get them to save hijacking this post and I look forward to your help and advice.

[Regenallotment Ambassador in reply to Baggiesfan]

Hijack away 🤗 we alllearn so much sharing and comparing 🌱

[silverbelle51]

Thank you for the sharing! I too have been exploring and happened upon a naturopath from AU who recommend checking reverse T3 and how it can affect the whole picture. She is at nikicleuet.com. Interesting and for me very relevant

[HealthStarDust]

Very pleased for you!

[Jaydee1507 Administrator]

Keeping everything crossed for you. The % through range for FT3 are on the high side and would be too much for me but you can still tweak as and when.

Free T4 (fT4) 21.3 pmol/L (12 - 22) 93.0%

Free T3 (fT3) 6 pmol/L (3.1 - 6.8) 78.4%

[Stourie]

I’m so pleased that what you’re doing is working for you. What is HRV ? Jo. X

[TiggerMe Ambassador in reply to Stourie]

HRV

[Stourie in reply to TiggerMe]

Thank you 😊. Jo xx

[Hunny_BEE]

it’s SO great to feel good! 👏🌻

[Polly91]

Well done Regenallotment

I too tried adrenal support a few months ago after I had a Lyme relapse & weirdly I think it’s helped my thyroid function? I need slightly less replacement now.

Thanks for sharing your story- as others have said it is inspiring and gives us all hope.