Help with possible Overactive Thyroid - Thyroid UK

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Help with possible Overactive Thyroid

Sadie_Deveraux profile image
4 Replies

Hi All,

I am very new to this, so any help is welcomed. I have now been referred to an Endocrinologist but have been borderline overactive for a while (GP wouldn't treat or refer until now.) My ESR and Immunoglobin are also heightened. I have always had blood tests late afternoon, can this affect things?

TSH: 0.63

T4: 24.8

ESR: 38 (up to 20 is normal)

Immunoglobin: 4.55 (0.8 - 2.8 is normal)

I have all the normal overactive symptoms - exhausted, weight loss, increased frequency for the toilet, anxiety, palpitations, brain fog etc. Most recently a throbbing to my throat - what's all that about?

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Sadie_Deveraux
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4 Replies
PurpleNails profile image
PurpleNailsAdministrator

Welcome

Please could you add ranges. Ranges vary between labs.

How long is a while? Over what precious of time? Do you have previous results to compare?

Your results show low TSH & high FT4 by most ranges, but this shows an elevation not dangerously high levels.

With Graves the most common cause of continuous hyper you would expect to see suppressed / undetectable TSH (<0.01) and FT4 is the 40s.

Although any continuous elevation will need to be addressed. So it’s good you are being referred to endocrinologist.

Your FT3 also needs to be tested, this is the active thyroid hormone, it can be out of balance.

ESR is non specific, you have inflammation occurring, but test cant pinpoint why or where, autoimmune is often a strong possibility.

Was it TSI thyroid stimulating immunoglobulin? The range doesn’t look right for that test.

As usually immunoglobulin is categorised to A, D, E, G, M. but these are less useful in terms of thyroid.

Your doctors should be establishing why your levels are showing hyper. Usually testing thyroid antibodies is first step.

TPO & TG antibodies are high with Hashimoto’s \ autoimmune thyroiditis. This can cause fluctuations in levels early on. Can also be positive with Graves.

If hyper Graves is suspected this must be confirmed by positive TSI or TRAb.

Treating low TSH / High FT4 as assumed hyper, without investigating why levels are high is not good approach. If rise is transient & will naturally drop anti thyroid medication will hasten the decline.

Sadie_Deveraux profile image
Sadie_Deveraux in reply to PurpleNails

I haven't had any further specific tests. My T4 has been creeping up and TSH going down over the last few years, however even though i have had symptoms and my Dad had Graves, my GP refused to refer me, they're only now referring me as i am now deemed to be out of their normal range, however they haven't told me the ranges.

The immunoglobulin that was abnormal was "A"

PurpleNails profile image
PurpleNailsAdministrator in reply to Sadie_Deveraux

A gradual increase such as this is what happened to me.

Over at least 4 years my frees were climbing, although my TSH became suppressed early on. My FT3 was similar to you level which just above range but FT4 was nearly double.

Is wasn’t closely monitored - I found all this out later when searching records.

I had ultrasound & had uptake scan to confirm a hyper functioning nodule, as antibodies were negative.

My father has thyroidectomy for hyper but wasn’t ever told the cause.

You can request a print outs of results via reception, most useful is to set up online access to GP records. See what’s access is available at your practice.

Hope your upcoming appointment goes well, & you get some answers.

SlowDragon profile image
SlowDragonAdministrator in reply to Sadie_Deveraux

To confirm Graves’ disease you need TSI or Trab antibodies tested

Also essential to test vitamin D, folate, B12 and ferritin

Vitamin levels very often low with Graves’ disease or Hashimoto’s

most endocrinologists are diabetes specialists

List of thyroid specialists and endocrinologists

healthunlocked.com/thyroidu...

Recommended that all thyroid blood tests early morning, ideally just before 9am, only drink water between waking and test

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)

Private tests are available as NHS currently rarely tests Ft3 or all relevant vitamins

List of private testing options and money off codes

thyroiduk.org/getting-a-dia...

Test TPO and TG antibodies for Hashimoto’s (and Graves’ disease)

Test TSI or Trab antibodies to confirm Graves’ disease

Medichecks Thyroid plus TPO and TG antibodies and vitamins

medichecks.com/products/adv...

Blue Horizon Thyroid Premium Gold includes antibodies, cortisol and vitamins

bluehorizonbloodtests.co.uk...

Only do private testing early Monday or Tuesday morning.

Link about thyroid blood tests

thyroiduk.org/getting-a-dia...

Tips on how to do DIY finger prick test

healthunlocked.com/thyroidu...

Medichecks and BH also offer private blood draw at clinic near you, or private nurse to your own home…..for an extra fee

Link about Graves’ disease

thyroiduk.org/hyperthyroid-...

Graves Disease antibodies test via Medichecks

medichecks.com/products/tsh...

Early stage Hashimoto’s can give results and symptoms similar to Graves’ disease before becoming increasingly hypothyroid

Link about Hashimoto’s

thyroiduk.org/hypothyroid-b...

Symptoms of hypothyroidism

thyroiduk.org/wp-content/up...

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