T4 and T3 levels dropping: I did some blood tests... - Thyroid UK

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T4 and T3 levels dropping

Alex_p profile image
10 Replies

I did some blood tests last week and noticed that my FT4 and FT3 levels have both dropped. I started taking folate and iron supplements and was expecting these to help with the thyroid levels, but apparently that’s not the case.

My current levels are:

FT4 15.8 (12-22)

FT3 5 (3.1-6.8)

Previous levels:

FT4 18.8 (12-22)

FT3 6.2 (3.1-6.8)

I’m currently taking 125mcg levothyroxine (Novothyral and Accord), 25mcg liothyronine (Novothyral and Tiromel 5mcg), iron 10mg BetterYou spray, methyl folate 400mg.

Should I increase the levothyroxine hoping that it will also increase the FT3?

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Alex_p
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10 Replies
SlowDragon profile image
SlowDragonAdministrator

Did you do both tests early morning and last dose levothyroxine 24 hours before test

Day before test did you split T3 as 3 smaller doses spread through the day and last T3 dose approx 8-12 hours before test

Alex_p profile image
Alex_p in reply to SlowDragon

I couldn’t take the last dose of levothyroxine 24h before the test because I’m taking Novothyral (which has both levo and lio) and I’m splitting so that I can take multiple doses of liothyronine. So my last levo dose was around 19 hours before the test).

Yes to the second question.

SlowDragon profile image
SlowDragonAdministrator

What were your most recent vitamin D, folate, B12 and full iron panel test results?

Alex_p profile image
Alex_p in reply to SlowDragon

Vitamin D was 105.

Alex_p profile image
Alex_p

Folate was 5.4 (no range provided), B12 440 (180-999), serum ferritin 24(13-150).

SlowDragon profile image
SlowDragonAdministrator in reply to Alex_p

Folate and ferritin were terrible

B12 borderline

So not surprised that, now you are improving low vitamin levels, you’re using thyroid hormones better

Probably now need small dose increase in Novothyral.

low folate and low B12

Rather than just taking folate…..supplementing a good quality daily vitamin B complex, one with folate in (not folic acid) 

This can help keep all B vitamins in balance and will help improve B12 levels too

Difference between folate and folic acid 

chriskresser.com/folate-vs-...

Many Hashimoto’s patients have MTHFR gene variation and can have trouble processing folic acid.

thyroidpharmacist.com/artic...

B vitamins best taken after breakfast

Thorne Basic B recommended vitamin B complex that contains folate, but they are large capsules.

(You can tip powder out if can’t swallow capsule) 

Thorne currently difficult to find at reasonable price, should be around £20 

If you want to try a different brand in the meantime, one with virtually identical doses of the ingredients, and bioavailable too, then take a look at Vitablossom Liposomal B Complex. Amazon sometimes has it branded Vitablossom but it's also available there branded as Yipmai, it's the same supplement

amazon.co.uk/Yipmai-Liposom...

or available as Vitablossom brand here

hempoutlet.co.uk/vitablosso... &description=true

IMPORTANT......If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 7 days before ALL BLOOD TESTS , as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

In week before blood test, when you stop vitamin B complex, you might want to consider taking a separate methyl folate supplement

Low ferritin is very likely going to take several months to improve.

Have you increased iron rich foods in your diet

Get full iron panel test done after 2-3 months on iron supplements and retest 3-4 times a year if self supplementing. It’s possible to have low ferritin but high iron 

Medichecks iron panel test 

medichecks.com/products/iro...

Iron and thyroid link

healthunlocked.com/thyroidu...

Excellent article on iron and thyroid 

cambridge.org/core/journals...

Posts discussing why important to do full iron panel test

healthunlocked.com/thyroidu...

healthunlocked.com/thyroidu...

Chicken livers if iron is good, but ferritin low

healthunlocked.com/thyroidu...

Shellfish and Mussels are excellent source of iron 

healthline.com/nutrition/he...

Heme iron v non heme

hsph.harvard.edu/nutritions...

Ferritin over 100 to alleviate symptoms 

healthunlocked.com/thyroidu...

Low Iron implicated in hypothyroidism 

healthunlocked.com/thyroidu...

Ferritin range on Medichecks 

healthunlocked.com/thyroidu...

healthunlocked.com/thyroidu...

We have received further information the lab about ferritin reference ranges. They confirm that they are sex dependent up to the age of 60, then beyond the age of 60 the reference range is the same for both sexes: 

Males 16-60: 30-400 ug/L

Female's: 16-60: 30-150

Both >60: 30-650 

The lower limit of 30 ug/L is in accordance with the updated NICE guidance and the upper limits are in accordance with guidance from the Association of Clinical Biochemists. ‘

Alex_p profile image
Alex_p in reply to SlowDragon

Thank you for all the details provided. I’ll do a full iron panel after the holidays. I was recommended liver and I try to have it regularly.

Regarding the vitamin B complex, I have tried some in the past but I was getting pimples. Taking B12 alone did not cause them so it was probably from one of the other Bs. I’m a bit weary of starting a B complex again because of this.

Noelnoel profile image
Noelnoel

Can’t offer advice but curious why you wanted help with previous thyroid levels, which to me look very good. Were you not feeling well?

Btw, I’m not for a second suggesting you didn’t need help with raising nutrients

Alex_p profile image
Alex_p in reply to Noelnoel

My previous results do look pretty good and I’m trying to get back to that :) I started to look at my vitamin levels because I was still getting pretty tired even with those thyroid levels and I did have anemia in the past. So the combination of good thyroid levels and getting supplements for what I’m lacking (iron and folate) has been the winner for me. I’ve felt like a new person. But lately I started feeling like something was off, which is why I did the tests.

ZoBo profile image
ZoBo

Hi Alex unfortunately im in the same boat so not able to give advice. However there are a great group of people on here have all the advice you need. Good luck!

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