“The conventional approach to treating Hashimoto’s Thyroiditis is to simply replace thyroid hormone with either synthetic or natural thyroid hormone.Today we want to share with you 3 ways this attack on self increases inflammation, therefore directly affecting your thyroid, your metabolism and your physiology.First, inflammation suppresses the hypothalamus – pituitary –thyroid (HPT) axis. One study showed a single injection of an inflammatory cytokine (TNF-alpha) reduced blood levels of TSH, T3, free T4, free T3 and TRH for 5 days. Thyroid medications might increase T4 and/or T3, BUT, they DO NOT address the effects on the HPT suppression.Secondly, inflammation decreases both the number and sensitivity of thyroid hormone receptors. If there are not enough receptors and they are not sensitive enough, it doesn’t matter how much thyroid medication you are taking. Your cells will NOT be able to use it and this is why your thyroid dose is concisely increased, with very little result.Last but not least is the idea that with the use of thyroid medication T3 will fall into balance. Not the case. The body has to convert the thyroid hormone, which takes primarily in the liver and gut in order for it to be used by the cells. A large population of people suffering with low thyroid (whether their labs show it or not) are being placed on synthroid (thyroxine (T4), the inactive form of thyroid. Unfortunately, states of inflammation and high stress, make it close to impossible to convert T4 to T3.The ONLY way to effectively address Hashimoto’s Thyroiditis is to reduce the inflammation, regulate the immune system and increase thyroid hormone conversion.”
What, if ANY of it is true or is it nonsense? To me, with my basic knowledge it sounds like scaremongering but I wanted to check with those of you who understand the disease.
Thank you.
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musicaljune
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musicaljune, So how can we know that what you've quoted is an accurate quote and hasn't been accidentally or deliberately misquoted? We have no way of checking. This is why forum guidelines say you should provide a link and/or source for anything you quote.
I'll start by observing that it seems to 100% ignore treating with liothyronine (T3).
It is so definitive that the ONLY way is by addressing inflammation without even mentioning liothyronine. Maybe (at least in his view) it has no role but at least explain!
Everything he says about elevated inflammation is correct evidenced by credible ongoing and regularly new research papers. That is why I’m always banging on about aiming to reduce thyroid antibodies which are effectively unwanted inflammation that risks causing dreadful damage.
The small amount of inflammation that prevents disease causing bacteria from infecting a cut finger (for example) is a healthy response that helps us heal but the low grade chronic inflammation that occurs in response to autoimmunity is unwanted.
When chronic inflammation occurs it is a dysregulation of the immune system that then struggles to keep us safe from usual offences such as viral or fungal infections, dysbiosis (gut imbalances), allergens such as gluten, and toxin exposure. This is why people with Hashi generally have multiple other issues that may develop into even higher levels of immune dysfunction such as MCAS, and why it can become difficult to move forward with recovery.
He has mentioned a few of the ways elevated inflammation can impair the good workings of our thyroid hormone replacement meds. Another way is the alteration to the thyroid enzymes (deiodinases) that activate/deactivate our T3, creating high amounts of inactive T2 and RT3, which fuels the situation further.
He hasn’t mentioned the aches & pains, the alterations to blood sugar levels, the encouraged weight gain around the middle associated with heart disease and increasing risk of a stroke. This is all unwanted low grade chronic inflammation which damages healthy cells and brain neurons, and causes oxidative stress that can encourage cancer, etc. . It is also one of the main drivers of the aging process.
Conventional medicine ignores the effects of Hashi until enough thyroid gland is destroyed to be replaced with Levothyroxine but this doesn’t address the underlying cause which will continue unless the triggers are removed and the inflammation consciously reduced.
I found eliminating gluten, optimising thyroid meds, B Vits, Vit D, fish oils and taking NAC & curcumin helpful. Also any fresh colourful foods and keeping hydrated will help quell inflammation.
Josh Rubens way of writing isn't great. For further clearer definitions you could read the Isabella Wentz books or anything by Datis Kharrizian.
Well said. Would any doctors place us on T3 if it was as cheap as Levo? I suspect that Big Pharma has enough power and influence that they would far prefer to keep us sick to aid their sales etc. in other things. Miserable if we don’t self treat.
“The conventional approach to treating Hashimoto’s Thyroiditis is to simply replace thyroid hormone with either synthetic or natural thyroid hormone.Today we want to share with you 3 ways this attack on self increases inflammation, “
I don’t think anyone would disagree about inflammation and how serious a problem it is but isn’t he saying that hormone replacement CAUSES inflammation or is it simply that his sentence construction is terrible?
As I said his way of writing isn’t great but he is trying to get across the damage Hashimotos inflammation can do in three direct ways.
Then he says taking thyroid hormone replacement meds (he doesn’t stipulate which) won’t necessary achieve adequate T3 levels, which we know from experience, and why this forum promotes the essential associated cofactors such as optimised iron & nutrients, which also contribute to controlling inflammation.
This is from their website - Josh and Jeanie Rubin - the basic starter downloadable ebook:
Balancing the Body Budget
An introduction to metabolic health.
Been on a health journey and tried everything? Worked with everyone? Chased symptoms and taken tons of supplements? Tried every diet? Confused and overwhelmed but still see little results?
It's time to learn to balance your body budget!
Over 30 pages long, this guide is packed with all of the knowledge and tools you need to create the foundation for healing.
Taken together, our findings indicate that chronic infusion of rats with TNF-alpha in a subpyrogenic and subanorectic dose induces a transient decrease of plasma T4 binding without affecting pituitary-thyroid activity and peripheral thyroid hormone metabolism.
Afraid that too much interest in selling (ebooks, supplements or anything else) undermines any faith I might have.
If you have been making a nice earning out of things, you are hardly going to remove them from your site if you find they are not such a good idea.
And, in these internet days, anyone can collect information and compile protocols, plans, etc. Some might even be excellent. But the primary aim is all too often sales even if some people benefit.
The same deduction could apply to NHS doctors who insist on sticking to their guns in the face of research which is undoing their views. They still receive their fat salaries no matter what.
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Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.
Endo says I don't have hashi, gyne says I do :/
how to speak to your GP about very low TSH
Hashimoto's. But doctors say to not treat. Why?
What is this doctor really saying about NDT and reference ranges?
Five weeks on dose increase, feeling worse.
