SERUM BLOOD TESTS: Good morning, I had a blood... - Thyroid UK

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SERUM BLOOD TESTS

Florah profile image
15 Replies

Good morning,

I had a blood test 4/3/22. Just checked my results online. These were tested- Serum vitamin B12 level, Serum ferritin level , Serum folate level.

The result is borderline & doesnt need any further action.

Shall I contact the GP and follow it up?

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Florah profile image
Florah
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15 Replies
Florah profile image
Florah

Also tested for these-Calcium profileSerum C reactive protein level

Liver function tests

Results- Abnormal but expected, no further action

SlowDragon profile image
SlowDragonAdministrator

Please add actual results and ranges

Was test done early morning, ideally just before 9am, and last dose levothyroxine 24 hours before test

Looking at previous posts

You have Hashimoto’s. Like many Hashimoto’s patients you started with transient hyperthyroid results and symptoms before becoming increasingly hypothyroid

Now on 100mcg Levothyroxine (accord brand)

ESSENTIAL to test vitamin D, folate, ferritin and B12

Add any results just done

Have you had coeliac blood test done yet

If not, request testing BEFORE considering trial on strictly gluten free diet

Florah profile image
Florah in reply to SlowDragon

Thank you SlowDragon

.
Florah profile image
Florah

SlowDragon Thank you

.
Florah profile image
Florah

Thank you SlowDragon

.
SlowDragon profile image
SlowDragonAdministrator in reply to Florah

Ferritin is deficient

See GP

You are likely to need iron supplements, possibly an iron infusion

Definitely a coeliac blood test too

Are you vegetarian or vegan

Do you have heavy periods (common when anaemic and/or hypothyroid)

Low iron and/or low ferritin frequently linked to hair loss

Heavy periods are classic sign of being hypothyroid and will lead to low iron and ferritin

cks.nice.org.uk/topics/anae...

In all people, a serum ferritin level of less than 30 micrograms/L confirms the diagnosis of iron deficiency

Also See page 7 on here

rcn.org.uk/-/media/royal-co...

Look at increasing iron rich foods in diet

Eating iron rich foods like liver or liver pate once a week plus other red meat every day , pumpkin seeds and dark chocolate, plus daily orange juice or other vitamin C rich drink can help improve iron absorption

List of iron rich foods

dailyiron.net

Links about iron and ferritin

An article that explains why Low ferritin and low thyroid levels are often linked

preventmiscarriage.com/iron...

irondisorders.org/too-littl...

davidg170.sg-host.com/wp-co...

Great in-depth article on low ferritin

oatext.com/iron-deficiency-...

drhedberg.com/ferritin-hypo...

This is interesting because I have noticed that many patients with Hashimoto’s disease and hypothyroidism, start to feel worse when their ferritin drops below 80 and usually there is hair loss when it drops below 50.

Thyroid disease is as much about optimising vitamins as thyroid hormones

healthunlocked.com/thyroidu...

restartmed.com/hypothyroidi...

Post discussing just how long it can take to raise low ferritin

healthunlocked.com/thyroidu...

Never supplement iron without doing full iron panel test for anaemia first and retest 3-4 times a year if self supplementing. It’s possible to have low ferritin but high iron

Medichecks iron panel test

medichecks.com/products/iro...

Iron and thyroid link

healthunlocked.com/thyroidu...

Posts discussing why important to do full iron panel test

healthunlocked.com/thyroidu...

healthunlocked.com/thyroidu...

Chicken livers if iron is good, but ferritin low

healthunlocked.com/thyroidu...

Heme iron v non heme

hsph.harvard.edu/nutritions...

Good explanations of iron

theironclinic.com/iron-defi...

theironclinic.com/ironc/wp/...

Excellent reply by Blearyeyed about iron in this post

healthunlocked.com/thyroidu...

SlowDragon profile image
SlowDragonAdministrator in reply to Florah

Request/insist on vitamin D test too

Highly likely to be deficient unless you are already supplementing vitamin D?

pubmed.ncbi.nlm.nih.gov/286...

Vitamin D deficiency is frequent in Hashimoto's thyroiditis and treatment of patients with this condition with Vitamin D may slow down the course of development of hypothyroidism and also decrease cardiovascular risks in these patients. Vitamin D measurement and replacement may be critical in these patients.

pubmed.ncbi.nlm.nih.gov/273...

Vitamin D insufficiency was associated with AITD and HT, especially overt hypothyroidism. Low serum vitamin D levels were independently associated with high serum TSH levels.

pubmed.ncbi.nlm.nih.gov/300...

The thyroid hormone status would play a role in the maintenance of vitamin D sufficiency, and its immunomodulatory role would influence the presence of autoimmune thyroid disease. The positive correlation between free T4 and vitamin D concentrations suggests that adequate levothyroxine replacement in HT would be an essential factor in maintaining vitamin D at sufficient levels.

ncbi.nlm.nih.gov/pmc/articl...

Our results indicated that patients with hypothyroidism suffered from hypovitaminosis D with hypocalcaemia that is significantly associated with the degree and severity of the hypothyroidism. That encourages the advisability of vit D supplementation and recommends the screening for Vitamin D deficiency and serum calcium levels for all hypothyroid patients.

SlowDragon profile image
SlowDragonAdministrator in reply to Florah

B12 is too low, but not low enough for GP to consider prescribing any supplements

Folate is mid range

supplementing a good quality daily vitamin B complex, one with folate in (not folic acid) This can help keep all B vitamins in balance and will help improve B12 levels too

Difference between folate and folic acid

chriskresser.com/folate-vs-...

Many Hashimoto’s patients have MTHFR gene variation and can have trouble processing folic acid.

thyroidpharmacist.com/artic...

B vitamins best taken after breakfast

Thorne Basic B recommended vitamin B complex that contains folate, but they are large capsules. (You can tip powder out if can’t swallow capsule)

IMPORTANT......If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 7 days before ALL BLOOD TESTS , as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

In week before blood test, when you stop vitamin B complex, you might want to consider taking a separate methyl folate supplement and continue separate B12

Low B12 symptoms

b12deficiency.info/signs-an...

With serum B12 result below 500, (Or active B12 below 70) recommended to be taking a B12 supplement as well as a B Complex (to balance all the B vitamins) initially for first 2-4 months.

once your serum B12 is over 500 (or Active B12 level has reached 70), stop the B12 and just carry on with the B Complex.

B12 sublingual lozenges

amazon.co.uk/Jarrow-Methylc...

cytoplan.co.uk/shop-by-prod...

healthunlocked.com/thyroidu...

SlowDragon profile image
SlowDragonAdministrator

Extremely common with Hashimoto’s to develop gluten intolerance

Before considering gluten free diet get coeliac blood test done via GP

With such low ferritin levels…..GP should be testing….even says to do so on those results

nice.org.uk/guidance/ng20/c...

1.1 Recognition of coeliac disease

1.1.1 Offer serological testing for coeliac disease to:

people with any of the following:

persistent unexplained abdominal or gastrointestinal symptoms

faltering growth

prolonged fatigue

unexpected weight loss

severe or persistent mouth ulcers

unexplained iron, vitamin B12 or folate deficiency

type 1 diabetes, at diagnosis

autoimmune thyroid disease, at diagnosis

irritable bowel syndrome (in adults)

first‑degree relatives of people with coeliac disease.

SlowDragon profile image
SlowDragonAdministrator

How long have you been on 100mcg levothyroxine

Have you had thyroid levels retested since starting on levothyroxine?

Always test early morning, ideally before 9am and last dose levothyroxine 24 hours before test

Florah profile image
Florah

SlowDragon i started take 100mcg of Levothyroxine 3/7/22

I haven’t had my levels checked yet, waiting for endro appointment

I had the test 8.50am and didn’t take Levo for 24 hrs

SlowDragon profile image
SlowDragonAdministrator in reply to Florah

So too soon to retest thyroid yet

Test after at least 8 weeks starting on 100mcg …and having started on a decent dose ….more like 3 -6 months time

GP should be looking at low ferritin levels though

And get vitamin D test and coeliac blood test

Florah profile image
Florah

SlowDragon thank you for all the info

Florah profile image
Florah

SlowDragon thank you. I will ask them to regularly complete these tests

jimh111 profile image
jimh111

You are a little bit unusual in that you have only one test out of range. Most people will find more than one when this number of tests (26?) are done. The chances of getting all the tests in range are about 26 in 100, less because some like ferritin are have healthy limits rather than a 95% reference interval.

However, your ferritin is low, it should be checked. Most women will have a ferritin below 30 but 15 is a bit too low. See originalText and originalText for typical ferritin levels. A ferritin of 40 ug/L is pretty good going for pre-menstrual women, fewer than half have a ferritin above this level.

The WHO state that one third of women of reproductive age are anaemic. Note these women do not exhibit the horror stories of hair loss etc. that are often put on commercial medicine websites. The WHO has a cut-off of 15 ug/L for iron deficiency originalText . So, you would be classified as iron deficient and should see your doctor for this. It may just be a matter of supplementing or change of diet but it makes sense to check it out.

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