medicheck results full panel - thoughts? - Thyroid UK

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medicheck results full panel - thoughts?

Fizzyinch profile image
12 Replies

I recently posted about advice on next steps following a recent hypothyroidism/ Hashimotos diagnosis.

I took the medichecks test to show FT3 as well as both antibodies (24 hours since last levothyroxine dose, no biotin, before 9am, fasted)

also took the Lloyd pharmacy coeliac test, negative for antibodies.

previous post here:

healthunlocked.com/thyroidu...

as per this post GP is concerned about low TSH

GP agreed to test Vit D and Ferritin at next thyroid test in 6 weeks.

Latest results here, never has T3 done before so have nothing to compare to, any advice much appreciated thanks!

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Fizzyinch profile image
Fizzyinch
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12 Replies
SeasideSusie profile image
SeasideSusieRemembering

Fizzyinch

as per this post GP is concerned about low TSH

TSH: 0.7 (0.27-4.20)

It's in range, at the lower end but in range, so what's your GP's problem?

You've had your pituitary removed so your TSH is not going to respond the same as someone who still has their pituitary.

As long as FT4 and FT3 are within range then there's no problem, it's FT3 that's the most important test.

Both your FT4 and FT3 are so low that they suggest an increase in your dose of Levo.

Fizzyinch profile image
Fizzyinch in reply toSeasideSusie

Hi, thanks for reply. The GP hasn’t seen this result, they are going off the tests I had done at the GP surgery which I put in my previous post (TSH 0.04)

I haven’t had my whole pituitary gland removed, I had a tumour removed from there however I take the point that TSH may not be totally accurate given it’s a pituitary hormone and my gland may not be normal.

When you say ‘they suggest an increase’ do you mean the GP?

SeasideSusie profile image
SeasideSusieRemembering in reply toFizzyinch

When you say ‘they suggest an increase’ do you mean the GP?

Your results - low FT4 and low FT3 - suggest an increase in your dose of Levo and your GP should look at these results.

SlowDragon profile image
SlowDragonAdministrator

How much levothyroxine are you currently taking

When was dose last increased

FT4: 14.6 pmol/l (Range 12 - 22)

Ft4 only 26.00%

FT3: 3.78 pmol/l (Range 3.1 - 6.8)

Ft3 only 18.38% through range

Helpful calculator for working out percentage through range

thyroid.dopiaza.org

Most people when adequately treated will have Ft3 at least 50-60% through range

How do you feel

This test shows you need dose increase in levothyroxine

Do you always get same brand

Fizzyinch profile image
Fizzyinch in reply toSlowDragon

Last dose increase was April.

SlowDragon profile image
SlowDragonAdministrator in reply toFizzyinch

Approx how much do you weigh in kilo?

Fizzyinch profile image
Fizzyinch in reply toSlowDragon

Around 71-72 KG approx.

SlowDragon profile image
SlowDragonAdministrator in reply toFizzyinch

So guidelines suggests likely to eventually need approx 112mcg per day

70kg x 1.6mcg = 112mcg

Some people need higher dose, some need lower

pathlabs.rlbuht.nhs.uk/tft_...

Guiding Treatment with Thyroxine:

In the majority of patients 50-100 μg thyroxine can be used as the starting dose. Alterations in dose are achieved by using 25-50 μg increments and adequacy of the new dose can be confirmed by repeat measurement of TSH after 2-3 months.

The majority of patients will be clinically euthyroid with a ‘normal’ TSH and having thyroxine replacement in the range 75-150 μg/day

(1.6ug/Kg on average).

The recommended approach is to titrate thyroxine therapy against the TSH concentration whilst assessing clinical well-being. The target is a serum TSH within the reference range.

……The primary target of thyroxine replacement therapy is to make the patient feel well and to achieve a serum TSH that is within the reference range. The corresponding FT4 will be within or slightly above its reference range.

The minimum period to achieve stable concentrations after a change in dose of thyroxine is two months and thyroid function tests should not normally be requested before this period has elapsed.

SlowDragon profile image
SlowDragonAdministrator

Looking at previous posts

18 days ago

Folate: 9.11 ug/L (>=5.38 ug/L)

B12: 370.0 ng/L (211.0 - 911.0 ng/L)

Are you now taking a daily vitamin B complex and separate B12 supplement too

No ferritin or vitamin D results?

How much vitamin D are you currently taking

Important to test vitamin D twice year when supplementing

Test folate, ferritin and B12 at least once year

Fizzyinch profile image
Fizzyinch in reply toSlowDragon

Hi slowdragon. Currently taking 75 levothyroxine. One 50 and one 25 which are different brands, I think the last few prescriptions have been the same brands- mercury and accord.

Vit D and Ferritin will be tested at GP in next check up as they missed them off and I had to request.

GP said B12 normal but read here it is too low…

please could you recommend a B12 and B- complex? It’s fine to take these together?

Thank you.

SlowDragon profile image
SlowDragonAdministrator in reply toFizzyinch

So request 25mcg increase in levothyroxine up to 100mcg

Bloods should be retested 6-8 weeks after any dose change or brand change in levothyroxine

Suggest avoiding Teva brand as upsets many people

supplementing a good quality daily vitamin B complex, one with folate in (not folic acid)

This can help keep all B vitamins in balance and will help improve B12 levels too

Difference between folate and folic acid

chriskresser.com/folate-vs-...

Many Hashimoto’s patients have MTHFR gene variation and can have trouble processing folic acid.

thyroidpharmacist.com/artic...

B vitamins best taken after breakfast

Thorne Basic B recommended vitamin B complex that contains folate, but they are large capsules. (You can tip powder out if can’t swallow capsule)

IMPORTANT......If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 7 days before ALL BLOOD TESTS , as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

In week before blood test, when you stop vitamin B complex, you might want to consider taking a separate methyl folate supplement and continue separate B12

Low B12 symptoms

b12deficiency.info/signs-an...

With serum B12 result below 500, (Or active B12 below 70) recommended to be taking a B12 supplement as well as a B Complex (to balance all the B vitamins) initially for first 2-4 months.

once your serum B12 is over 500 (or Active B12 level has reached 70), stop the B12 and just carry on with the B Complex.

B12 sublingual lozenges

amazon.co.uk/Jarrow-Methylc...

cytoplan.co.uk/shop-by-prod...

healthunlocked.com/thyroidu...

How other member saw how effective improving low B vitamins has been

healthunlocked.com/thyroidu...

Fizzyinch profile image
Fizzyinch in reply toSlowDragon

Super helpful, thank you!

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