Medicheck results : Good afternoon I’ve... - Thyroid UK

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Medicheck results

Jocarter profile image
10 Replies

Good afternoon

I’ve attached a copy of a recent medichecks blood test. This is the first time I’ve used them as I usually get tested by my gp but as they only test tsh & t4.

Last year (March) my gp agreed to an increase in levothyroxine from 50mcg to 75mcg as my tsh was 5.79 (range 0.34-5.6) only just over but I was feeling dreadful so they agreed to the increase

I’ve been feeling rough again lately (seems to always be at this time of year) and the medichecks results show increased antibodies,

Do you think the gp would do anything if I showed them these results - I’ve realised now there’s a lot more to having an under active thyroid than just taking levothyroxine

Thanks

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Jocarter profile image
Jocarter
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SlowDragon profile image
SlowDragonAdministrator

Was this test done early morning, ideally before 9am and last dose levothyroxine 24 hours before test

Which brand of levothyroxine are you currently taking

Do you always get same brand

See GP and request 25mcg dose increase in levothyroxine up to 100mcg daily

TSH should be under 2 as an absolute maximum when on levothyroxine

gponline.com/endocrinology-...

Replacement therapy with levothyroxine should be initiated in all patients to achieve a TSH level of 0.5-2.0pmol/L.

NHS England Liothyronine guidelines July 2019 clearly state on page 13 that TSH should be between 0.4-1.5 when OPTIMALLY treated with just Levothyroxine

Note that it says test should be in morning BEFORE taking levothyroxine

Also to test vitamin D, folate, B12 and ferritin

sps.nhs.uk/wp-content/uploa...

Graph showing median TSH in healthy population is 1-1.5

web.archive.org/web/2004060...

Aim is to bring a TSH under 2.5

UK guidance suggests aiming for a TSH of 0.5–2.5

gp-update.co.uk/SM4/Mutable...

Persevere - have all guidelines printed and be ready to quote them

healthunlocked.com/thyroidu...

If these dose by weight guidelines help, can also use these to push for next dose increase

NICE guidelines on full replacement dose

nice.org.uk/guidance/ng145/...

1.3.6

Consider starting levothyroxine at a dosage of 1.6 micrograms per kilogram of body weight per day (rounded to the nearest 25 micrograms) for adults under 65 with primary hypothyroidism and no history of cardiovascular disease.

Also here

cks.nice.org.uk/topics/hypo...

gp-update.co.uk/Latest-Upda...

Traditionally we have tended to start patients on a low dose of levothyroxine and titrate it up over a period of months. RCT evidence suggests that for the majority of patients this is not necessary and may waste resources.

For patients aged >60y or with ischaemic heart disease, start levothyroxine at 25–50μg daily and titrate up every 3 to 6 weeks as tolerated.

For ALL other patients start at full replacement dose. For most this will equate to 1.6 μg/kg/day (approximately 100μg for a 60kg woman and 125μg for a 75kg man).

If you are starting treatment for subclinical hypothyroidism, this article advises starting at a dose close to the full treatment dose on the basis that it is difficult to assess symptom response unless a therapeutic dose has been trialled.

BMJ also clear on dose required

bmj.com/content/368/bmj.m41

Have you had coeliac blood test done?

High thyroid antibodies confirms autoimmune thyroid disease

GP should test all autoimmune thyroid patients for coeliac disease

crimple profile image
crimple

Jocarter, once you are being treated with thyroxine your TSH should be less than 2 and for some people less than 1. After your last increase to 75mcgm levo you should have been tested again after 6-8 weeks not left for nearly a year!!! Yes, you need an increase to 100 mcgm and then another test after 6-8 weeks. Your GP is clearly only looking at the TSH and thinking you are in the range rather than taking note that you are not feeling well due to being undertreated. You also have very high antibody levels, so that's Hashimotos! No doubt you weren't tested for that by GP.

Have you tried a gluten free diet?

Slow dragon has posted some useful references to quote at the GP if they won't increase your medication. Good luck!

Gingernut44 profile image
Gingernut44

Another thing to mention- the top reference for TSH is far too high. I can’t imagine anyone who has a healthy, fully functioning thyroid would have a TSH as high as 5.6!

humanbean profile image
humanbean in reply toGingernut44

I can’t imagine anyone who has a healthy, fully functioning thyroid would have a TSH as high as 5.6!

You should find this link of interest:

healthunlocked.com/thyroidu...

Gingernut44 profile image
Gingernut44 in reply tohumanbean

Blimey humanbean, my reply to that post was 2 months ago!!!I will just add that I had a TSH added to a blood test for a completely separate issue, way before my thyroid problems- I think it was the Lab who did it, I can’t imagine my GP actually asking for it. I was 69 at the time and my TSH was 0.75 Of course, I didn’t know that until I requested access to my blood tests about 3 years ago.

Considering that Levothyroxine is the third highest prescription in UK (or is it the world) every surgery should have at least one GP/Nurse who knows what they’re talking about, after all, most of them have a diabetic GP/Nurse. Perhaps it’s because it’s men who suffer more with diabetes and women with thyroid dysfunction- or am I being cynical 🤨

humanbean profile image
humanbean in reply toGingernut44

Ooh, I hadn't noticed the date. The OP has started a more recent thread and I must have looked up OP's posting history to get to this one without realising what I was doing.

Bet you didn't want to know all that. :D

Gingernut44 profile image
Gingernut44 in reply tohumanbean

It’s good to be reminded 😜

Jocarter profile image
Jocarter in reply tohumanbean

At one point it was 5.62 (range was up to 5.6) and as i was feeling ill i called up and spoke to a locum - they said that they wouldn't increase my levothyroxine as it was only just out of range !! I wish i had known about this forum then !

humanbean profile image
humanbean in reply toJocarter

I used to have similar conversations so I can empathise and sympathise. My TSH would be slightly over range but my Free T4 and Free T3 were both really low in range. :(

Jocarter profile image
Jocarter

Thank you for your replies.

The information you have provided is extremely helpful , I will make an appointment with my GP and I will keep you informed how I get on x

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