This paper discusses the role of adequate selenium and vitamin D in controlling thyroid disease. I've added their conclusion here. I doubt it will surprise posters on TUK
Front. Endocrinol., 15 June 2022 | doi.org/10.3389/fendo.2022....
Add-On Effect of Selenium and Vitamin D Combined Supplementation in Early Control of Graves’ Disease Hyperthyroidism During Methimazole Treatment
Daniela Gallo1*, Lorenzo Mortara2, Giovanni Veronesi3, Simona AM Cattaneo4, Angelo Genoni5, Matteo Gallazzi2, Carlo Peruzzo6, Paolo Lasalvia3, Paola Moretto7, Antonino Bruno2,8, Alberto Passi7,9, Andrea Pini9, Andrea Nauti9, Maria Antonietta Lavizzari9, Michele Marinò10, Giulia Lanzolla10, Maria Laura Tanda1, Luigi Bartalena1 and Eliana Piantanida1*
In conclusion, the results of this study in a cohort of newly diagnosed, consecutive GD patients, with borderline low Se levels and VitD insufficiency, suggest that i) Se and VitD supplementation facilitates restoration of euthyroidism during MMI treatment; ii) Se and VitD supplementation boosts the improvement of QoL during MMI treatment. It is reasonable to propose that Se and VitD status be assessed at diagnosis of GD, and Se and VitD supplementation be offered at adequate and safe dosages if even a slight deficiency of these micronutrients is found.