I recently read this statement on the STTM blog.
"The one thing researchers do know is “thyroid treatment isn’t optimal–and may not work–if you do not have adequate vitamin D for the crucial final metabolic step, which takes place at the site where thyroid hormone actually works. This happens inside the nucleus of the cell. Vitamin D needs to be present at sufficient levels in the cell in order for the thyroid hormone to actually affect that cell. That is why vitamin D is so crucial.”
Can anyone with knowledge or experience confirm this? I've been struggling with hypo symptoms for about four years. I gained 50 pounds last year alone, despite watching my diet and working out 3-4 times per week. I've been on various doses and combinations of t3 and t4. Ranging from 35mcgs of t3 moving up to 125mcgs, and 125mcgs of t4 only to a combination of 180 mcgs of t4 and 25 mcgs of t3. But throughout this whole ordeal, I've struggled with low vitamin D. It's been as low as 18, and as high as 27, with a reference range of 30-100 NG/ML. Could it be that simple? Also, I recently had test for TPO antibodies, and it came back 12IU/ML, with a reference range of 0-30. At what point is one considered to have Hashimotos? Thanks.