MTHFR Test - B12, Vit D and Folate supplements.... - Thyroid UK

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MTHFR Test - B12, Vit D and Folate supplements....

jamiebgp profile image
4 Replies

Hi guys,

Hashimotos (armour NDT 2.25 Grains per day puts me at 0.9 TSH(0.27 -4.2) and 5.2 T3 (3.1-6.8) but Ive still had very poor mental health, anxiety, depression, mood swings, fatigue, confusion as well as a huge uplift in migraine.

Recently NHS bloods came back with

B12 356 pg/ml (191-663)

Serum Folate 3.3ug/l (4.5-32.2)

They wouldn't test Vit D

I have been asked to do a MTHFR test by Country Health

countryhealth.co.uk/product...

But is very expensive and so I was looking at alternatives.

My thinking is that the low folate and lowish B12 could be screwing everything up and my understanding is the MTHFR would just confirm if there is an issue, am I right.

The GP called today to prescribe folate but im wondering whether a specific product as well as B12 and Vit D supplementation maybe more suitable for my condition and whether addressing these nullifies the test for MTHFR so hence the advise required please.

Thank you

Jamie

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SlowDragon profile image
SlowDragonAdministrator

If you happen to have done DNA test via Ancestry for family history reasons you can get health evaluation of DNA here

Approx £15

Obviously more expensive if need to start from scratch

mthfr-genetics.co.uk

Are you currently taking supplementing vitamin D

Test twice yearly via NHS

vitamindtest.org.uk

Aiming for vitamin D at least around 80nmol and around 100nmol maybe better

SlowDragon profile image
SlowDragonAdministrator

mthfr-genetics.co.uk/nutrac...

This one is £149

radd profile image
radd

jamiebgp,

Mutated MTHFR can cause a while load of problems beyond folate & VitB12, effecting hormones & neurotransmitters serotonin/dopamine (just investigating again coz of my RLS).

But I think if you don’t want the MTHFR test then just supplementing the methylated forms would suffice. It’s just easier to prevent issues such as elevated homocysteine, or a build up of oestrogens, and easier to deal with them if you know you have impaired MTHFR.

Ensure to get the L-forms, ie L-methylfolate, L-methyltetrahydrofolate, L-MTHF, L-methylfolate calcium, etc

jamiebgp profile image
jamiebgp

Hi again and thank you for the advice. I’ve joined the other groups and I’ve ordered all my vitamins and supplements, I’m now looking at the juggle act of when to take them so they do not interact with the Armour NDT or each other, can anyone advise please?I’m split dosing my Armour at 6:30am and 12:00pm

My supplements and vitamins are:

Folic acid 5mgs (prescribed as under)

Vit D 3000 spray and K2 tablets

B12

magnesium

Selenium

My thoughts are to take the armour first dose at 6:30am.

Breakfast at 9:00am with Vit D, Folic Acid, Selenium and B12.

Armour 2nd dose 12:00pm

Magnesium before bed.

Does this look about right?

Best

Jamie

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