So I’ll give background. 12yrs Hashi -hypo. 11yrs of Levo only. Poor convertor so added T3. I’ve been on combined treatment for just over a year and these last 3wks I’ve had hypo symptoms. I’ve gone from 0% through range FT3 to 94% through range and have felt fantastic for a year 🥳
FT3
Jan - 6.58 (3.1 - 6.8)94% through range
July - 5.61 (3.1 -6.8) 67% through range
Ferritin
Jan - 84.8
July - 84.8 (13 -150)
Folate
Jan - 5.8
July - 7.04 (3.89 - 19.45)
Active B12
Jan - 65.3
July - 124 (37.5 - 187.5)
Vit D
Jan - 47.2
July - 64.5 (50 - 175)
I have not been consistent with my supplements and I had changed my routine to try and do better.
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NWA6
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Presumably tested as early as possible in morning before eating or drinking anything other than water and last dose levothyroxine 24 hours before test and last 1/2 or 1/3rd T3 before test?
I recently dropped my levothyroxine 25mcg (from 125mcg to 100mcg) intending to increase T3 by 5mcg
Ft4 had been creeping up at each test ....last test Ft4 was nudging right at top of range .....loads of hypo symptoms... carpal tunnel, painful thyroid etc etc
Astonished to get dramatic improvement in symptoms just by lowering levothyroxine by 25mcg
So far...four weeks on ...still not added any extra T3 .....going to wait now and retest in 6-8 weeks
So for me it appears I get symptoms if on too much levothyroxine as well as too little
I do have Dio2 gene.
Could never tolerate more than 125mcg, (Guideline on dose by weight suggests I should be on 137mcg on just levothyroxine)
Before T3 was added....always felt better on 100mcg ....but then Ft3 would drop below range
That sounds good. Yes I’m similar with high FT4, I had tried to raise it before I realised that I’m not a good convertor and actually I’d become hyper, insomnia, palpitations and anxiety (and yet my FT3 was O%)
I forgot I had the blood test, one of my symptoms 😬 So I took my Levo at 11pm so I have a high FT4 😩 22.7 (12-22)
hey hey, your ft3 has dropped quite a bit, enough to give you symptoms.
Ft4 is controversial, I have been reducing mine, similarly to SlowDragon I felt hypo recently having it around 70-80%.
Your vit D may need a little helo, but I personally think your hypo symptoms come from thyroid not vits.
Yeah the results are a kick up the bum re Vits to stop being so lackadaisical about them. I have stupid RLS and painful forearms which are good indicators that I’m not optimal 😩
I have RLS now too, from hypo, hate this symptom with severe insomnia so I really symphatise can you increase your t3? Re: ft4, I wouldn't worry too much, if you look at charts, it peaks only within a couple of hours, so your result is not far from the truth.
well, my own personal experience shows that for some weird reason consistent high ft3 somehow raises my ft4, this is how I have become weirdly overmedicated yesrs ago, suddenly my ft4 was high from midrange after several months. SlowDragon above says she had similar experience. Ft4 doesn't fluctuate during the day widly at all.
It's probably not that weird if you think about it. More T3 in the tank means your metabolism works better and so your thyroid is perhaps capable of making more T4 of it's own. Just a theory, but it does make sense from an energy point of view.
Yes, you are right and also when you add t3 it stimulates progesterone production, which raises thyroxine in blood. So you end up needing less t4 in a pill form
Restless leg syndrome. I don’t know what it’s like for anyone else but for me it’s like a cobra is wound round my left leg, squeezing. The only way for me to feel better is to constantly move my leg or sleep with a tens machine on it.
One thing I didn't mention in that reply on the subject of potassium is that I do take a potassium supplement - I bought a bag of potassium bicarbonate, and I take quarter of a level teaspoon mixed in water almost every morning, along with the same amount of sea salt and magnesium citrate powder. (I take the same amount of magnesium only, in the evening.) It isn't the nicest concoction to swallow but it's worth it.
Another possible cause of cramp is low calcium. I always forget to mention that because my calcium levels are always high in range so I would never need or want to supplement it.
Looked on net (I'm a bimbo) that low iron in brain can be a cause. Have you tried Spartone iron supliment. It is like iron water and is said to be better absorbed and not cause constipation.
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can you increase your t3? Re: ft4, I wouldn't worry too much, if you look at charts, it peaks only within a couple of hours, so your result is not far from the truth. 
Titrating Block and Replace
A year and still not right!! T3 needed or not!?
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Low FT4 With Normal FT3 and TSH?
