Our study shows that hypothyroidism significantly increases serum creatinine levels and decreases both urea/creatinine ratio and creatinine clearance. The reduced GFR was corrected after treatment of hypothyroidism.
Chronic kidney disease (CKD) is characterized by a low T3 syndrome which is now considered a part of an atypical nonthyroidal illness. CKD patients also have increased incidence of primary hypothyroidism and subclinical hypothyroidism.
Suggests you are not correctly treated for your Hashimoto’s
Extremely common to have low Ft3 when just taking levothyroxine
How much levothyroxine are you currently taking
Do you always get same brand of levothyroxine
What vitamin supplements are you currently taking
When were vitamin levels last tested
For full Thyroid evaluation you need TSH, FT4 and FT3 plus tested. Also EXTREMELY important to test vitamin D, folate, ferritin and B12
Recommended on here that all thyroid blood tests should ideally be done as early as possible in morning and before eating or drinking anything other than water .
Last dose of Levothyroxine 24 hours prior to blood test. (taking delayed dose immediately after blood draw).
This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip, best not mentioned to GP or phlebotomist)
Private tests are available as NHS currently rarely tests Ft3 or thyroid antibodies or all relevant vitamins
I recently had a DNA Blue Horizon thyroid genetic test. It showed that my DIO2 thyroid hormone activation was ‘TC’ (not sure what this means) which is associated with anxiety and depression in those taking T4 for hypothyroidism. I can confirm this is correct for me! It said this could be overcome with T4/T3 therapy.
It also gave a CC result with normal DIO2 activity which is not associated with any impact on thyroid hormone ratio. It said adequate levels of iodine and selenium are required for optimal functioning of the gene.
Both above were amber results which indicates one genetic variant present, and has a potentially mild negative impact.
The other Amber results I obtained were for TNF-a inflammation which was AG score showing my increased likelihood of overactive inflammatory immune response. This means I am at increased risk of chronic inflammatory and autoimmune conditions including Hasimoto’s (which I have).
The other amber score was forTSHR thyroid stimulating hormone receptor which also had an AG score. This is common in people with Graves’ disease and is linked to the presence of thyroid stimulating hormone receptor antibodies associated with developing GD. I don’t have GD yet.
I didn’t understand much of this when I obtained the DNA report. I would be grateful for your thoughts on the report.
Thank you again for responding. I appreciate your knowledgeable comments.
Prostate: I added TSH test to hubby's regular PSA test which was usually raised. Diagnosed late in life at 73 with Hashimotos - now 81. Once well treated with T4 - now T3 - his PSA dropped and remains low. We cannot help thinking there is a connection ..
Thanks Marz. That is reassuring. However I’m thinking that trying T4 with T3 as this might improve my T3 T4 ratio and help my kidney function which is my present worry.
I agree Blue Horizon test results are unintelligible to the layperson. I should have contacted Blue Horizon at the time and asked for clarification. I think I will do that now. It is bad of Blue Horizon not to provide proper understandable clarification.
It’s a shame that Blue Horizon don’t offer that as an option. I would’ve bought that option to know more about the results with a view to improving my health and quality of life.
I agree. From reading online about healthy kidney diets, I am dropping chicken from my diet straight away. I don’t eat beef. I’m hoping fish will be okay.
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