On novothyral

[tamina786]

My private consultant gave me novothyral t4 75 and t315 which is combination but before starting my

t4 was below range 9.3

t3 was 2.8

tsh was 11

I start taking it and in 4 weeks my

t4 was 14

t3 was 4.6

tsh was 0.03 ,

also was getting symptoms of shaky legs anxiety, so my gp put me back on levothyroxine and I told them I feel unwell cause I get all hyper symptoms on them , I need advice what shall I do but felt better on novothyral until my tsh suppressed cause i get all over medicated symptoms, has any one tried novothyral please guide me

[Wetsuiter]

I believe that testing 4 weeks after a dose change is too early.

Also, I'm not too sure what the official definition is of Suppressed TSH, but yours doesnt seem that low.

When you say 'hyper' symptoms, what makez you say that?

[tamina786 in reply to Wetsuiter]

The reason I said that because get shaky legs and palpitation and sweating alot

[Wetsuiter in reply to tamina786]

I believe they can be symptoms of hypothyroidism too

[greygoose]

Can you put the ranges, please. Ranges vary from lab to lab, so we need those that went with your results. We can't comment without them.

[miriammsm]

You are probably taking too much of one of them. Novothyral didn't work for me because of the proportion T4//T3. Now I am taking Levo+Liothryronin (T4/T3), but separately, so that you can raise one of them without raising the other. MUCH better. And works better on fT3 too.

(Neither T4 alone nor T3 alone worked for me.).

[tamina786 in reply to miriammsm]

Hey thanks alot how much are you on at present and personal question how much you weigh because that's how you get a dose right but I'm so fed up and so poorly I just want a good day I've was diagnosed with graves and im hypo, but had near total thyroidectomy, could you tell me how much you take and please guide me , because I was thinking to take half and quarter of novothyral so it will be 11.25 t3 and 56 t4

[miriammsm in reply to tamina786]

Hallo, I am about 70kg and taking about 112mcg T4 and 5-10mcg T3. But everyone is different. The amount depends also on other hormonal interactions and other factors. I have secondary hypothyroidism which is quite rare.

[pennyannie]

Hey there again,

As you will see from our post yesterday your own thyroid would have been producing T3 and T4 on a daily basis, so it does make sense to replace like with like and prescribing you a combination of these two essential thyroid hormones seems a sensible first step.

It is a fine balance, but roughly speaking a fully functioning thyroid would be supporting you on a daily basis with about 100 T4 + 10 T3. As previously discussed if your vitamins and minerals are not optimal your body will struggle to utilise these vital hormones.

Did you private consultant run any tests before he prescribed the Novothyral ?

Do you have any other results you can share with us ?

When did you have your thyroid surgery ?

[Hashihouseman]

Yes that is suppressed and probably not good unless you have a specific clinical need like thyroid gland tumour risk

Based on my own combo therapy and some scientific / research data that ratio of t4 t3 in the pills you were prescribed isn’t physiological - 15 t3 is probably too much; 5 or even 2.5 is a better start point and may well be all you need.

Healthy thyroid production rates give the equivalent of about 100 mcg t4 and 5-7 mcg t3 doses, with resulting ft4 about 15-16 and ft3 about 4.5 and TSH about 1 - 1.5.

Seems sensible to at least aim at those figures and see how we feel and test after a couple of months.

[Mikka]

You can get symptoms like that if adrenals need supporting or vitamins/iron is low. You won’t know if that was the correct dose if any of the above are not optimal.