I put on weight with T3. My weight would just jump like 5lbs overnight in the weeks after a dose increase. A side effect of T3 is weight gain as well as weight loss, so I am obviously one of the unlucky ones. I am lucky that I have found 40-50mcg divided into 3 doses is best in terms of alleviating my Hypo symptoms but I have stayed overweight, although the weight gain has ceased now I've found the therapeutic range for me. The Thyroid Patients Manual suggests that 50-80mcg is the level at which most people feel a significant alleviation in symptoms so maybe look at adjusting dose in this range while also considering the variables below.
Gluten Free has also significantly helped my symptoms of exertion fatigue and chronic inflammation, I was reluctant to go down this route for a while but it has improved my symptoms as well as bringing my CRP (inflammation marker in blood) into range and reducing my TPO antibodies into a range so I actually see where I am up to.
Have you tested your vitamin levels to work towards getting them to optimal levels.
I didn’t realise for sometime that T3 can cause weight gain but I have been taking 75mcg (3 x 25mcg spaces through the day) and I started to feel overmedicated so reduced the dose gradually to 62.5mcg and then 50mcg. Each drop took a few weeks to adjust to but I now find I feel the same but I am able to loose weight with low carb and no sugar. Hope this helps.
The blog Tired thyroid (tiredthyroid.com) claims that too much T3 causes insulin resistance which in turn leads to weight gain. I had never read that anywhere else - most blogs and forums and books on T3 only mention its fat-burning abilities - but it seems T3 can cause weight gain in some people - especially if they are on too much for their needs.
I have put on a lot of weight on NDT which also contains T3 so taking T3 is NOT a guarantee for weight loss.
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