Cynomel 0.025 mg is ok to start with after slow T3?

[ziv1979]

Hi,

I have finished taking slow T3 after 3 months along with my Levo 150 mg. The effect was good but not good enough. Since I can only get it privately and the cost is very high, my doc prescribed me with Cynomel (Sanofi) 0.025 mg to start with half a pill for 3 days and increase slowly. I guess my questions would be:

1. what’s the differences I should see between slow T3 vs Cynomel?

2. Will I be able to loose some weight on Cynomel? (on slow T3 I was sweating a lot and felt bloated a bit)

3. Does Cynomel works as Cytomel?

4. Does Cynomel can be taken more then 0.025 mg?

I need some instructions Appreciate the feedback.

Ziva

[greygoose]

1 The difference is... I take it by 'slow', you mean 'slow release' T3? Well, they're both T3, and T3 is T3. So, basically, you shouldn't feel any difference at all. The only thing is, with slow release there was never any guarantee how much you would absorb. With Cynomel you may absorb more. But, there are no guarantees of anything. Another difference that you may need to split the dose into 2 or 3 with Cynomel, depending on how much you take. But you can take it all in one go if that suits you better.

2. You have as much chance of losing weight with Cynomel as any other T3, but it depends how much you take - among other things. You don't say how much slow release you were taking. But, as a general rule, T3 is not a weight-loss drug.

3. Both Cynomel and Cytomel have T3 as the actvie ingredient. So, yes, in theory. But the fillers will be different and different people react differently to different fillers.

4. You can take as much Cynomel as you need. Take it on an empty stomach, just as you would levo, and leave at least one hour before eating or drinking anything other than water, etc.

[ziv1979 in reply to greygoose]

Thank you for your prompt reply!

I was taking 10mg of slow T3 .

Can I take both levo 150 and Cynomel 0.025 at the same time?

[greygoose in reply to ziv1979]

Indeed you can.

But, I thought you were taking half a 25 mcg tablet - i.e. 12.5 mcg. If you were only taking 10 mcg (NOT mg) slow release T3, then going up to 25 mcg would be too much of an increase.

[shaws Administrator]

One of thyroiduk's Advisers (now deceased) was an expert in the use of T3. He wouldn't recommend slow-release T3 as he stated that T3 has to saturate all of our T3 receptor cells and it then sends out 'waves' that can last one to three days. I did try this once only. I took T3 and for the next two days didn't take any at all and the one dose did last me for three days. I take one daily dose of T3 when I get up with one full glass of water and wait an hour before eating.

[ziv1979 in reply to shaws]

So you take 1 pill every three days? What’s the dosage?

Can I take it with my levo?

[greygoose in reply to ziv1979]

No, I don't think that's what shaws is saying. And, I don't think that that was what Dr John Lowe meant, either - she was referring to Dr John Lowe.

Slow release refers to the way it goes from the gut into the blood. It doesn't have any connection with the way it is taken up by the cells. And you couldn't take any form of T3 once every three days, you have to take it every day whether it's slow release or normal T3. My understanding is that Dr Lowe was talking about the effect it has once it gets into the cells and stays there for about three days.

[shaws Administrator in reply to ziv1979]

greygoose is right, I didn't mean that I take T3 every three days. I take it daily but I did an experiment that Dr John Lowe stated, with one daily dose it saturates our T3 receptor cells which can last between one to three days but he did mean to take one daily dose. I doubt most endocrinologists are unaware as they seem not to understand, either NDT or T3, at all. Especially as they've been instructed not to prescribe either of these latter two which many thyroid sufferers found helpful and reduced their symptoms.

[unblocktheplane]

Dear Ziva,

I have switched from 150mcg T4 (levothyroxine) to T3 SR (sustained release from a compounding pharmacy) for more than two years. Getting the dosing right was really tricky and took a very long time.

The reason for the switch was that I became symptomatic again. It looks like this was the result of a second autoimmune condition, hypocortisol, rather than any change to my Hashimoto’s.

Unfortunately, neither of these are accurately measured by lab testing. The determination of wellness is measured by body temperature readings, heart rate & blood pressure.

I know I’m not answering your question yet. Yes, Sanofi’s Cynomel will work the same as Pfizer’s Cytomel. They only come in two flavours, 25 mcg & 5 mcg. And they’re really expensive! So unless your insurance covers your prescription, Cynomel is available in different brands, too, as a greatly reduced cost.

Here are my suggestions. Buy Paul Robinson’s three books, Reovering with T3, The CT3M Handbook, and The Thyroid Patient’s Manual. You may wish to give them to your doctor, too, as he’s open to T3. Take a look at Paul’s blog: paulrobinsonthyroid.com.

Join the RT3-Adrenals group here: groups.io/g/RT3-Adrenals. The group’s moderator, Ann, is excellent at answering all your questions.

The important part is the balance between your levo T4 and your T3. If your SR T3 was working for you, you might want to divide the same dose of Cynomel into two to five divided daily doses. These small changes can really only be accomplished by a compounder. The pills are very hard to split other than in halves

Hope this helps.

Good health,

CJ