So, I have had my private appointment with endo from the list. He was kind and considerate, talked to me as if I was a little child, with patience and slightly condescending... Explained how pituitary produces TSH and how T4 signals back to pituitary... bla bla... He looked at my private thyroid blood test and said it was meaningless... Raised Anti thyroid globulin antibodies ( 545) meant nothing and definitely not an indication of Hashimoto's ( ???). According to him body produces antibodies to all sorts of tissues, which does not mean autoimmunity at all...hmm... My FT4 ( 14.1/ range 12-22)and FT3 (4.3/ range 3.1-6.8) are within normal range and the fact that they are at lower end means nothing. How about the fact that I feel all the symptoms of hypothyroid? Persistent low body temperature- thermometer is inaccurate, low energy levels - you must be stressed and overworked, depressed and unmotivated - what do you do for work?, no sex drive - smirk, when did you have your menopause? ! You can't win! Eventually, rather reluctantly he prescribed thyroxine 25mg. Now I am not sure and confused if I should take it at all? May be I am mad and should just accept I am getting old... Shall I try it for a couple of months? I do not have any experience with this meds and I heard that NDT works better for most people...I would appreciate your opinions and may be some encouragement.