Adrenavive ll v Pregnenolone or both for adrena... - Thyroid UK

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Adrenavive ll v Pregnenolone or both for adrenal insufficiency

fizzygig profile image
11 Replies

My Regenerus cortisol saliva test showed low morning cortisol just outside normal with other 3 samples being at low end of range & low DHEA ( have posted results previously with Phase 3 adrenal insufficiency. GP confirmed low morning serum cortisol with referral to endo (18 wk wait for appointment. I have corrected my vit levels with good quality B12/folate ( sublingual) Vit D/K2 mouth spray, zinc, selenium, magnesium maleate. Now need to retest Vits & thyroid to see if this has had any impact. I have done considerable reading around adrenal support & feel that Adrenavive may help.? After reading DrMyhills website feel Pregnenolone may be the answer? My dilemma is which should I try first or can I take them together ? Have any members experience of these or advice to offer?

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Taking any "adrenal support medication" prior to the Endo appointment will mess up any tests he may want to do. You could end up being discharged by the endo with no real diagnosis. However if the Endo doesn't think that you have adrenal insufficiency then you could take them if you felt they would help.

fizzygig profile image
fizzygig in reply to

Thanks for your very sensible advice, makes sense... I just want to feel well again

CornishChick profile image
CornishChick

Hi

I had similar results and Dr Myhill advised that I started on Adrenavive. You have to take lots off temperatures (see her website), and increase gradually until they stabilise. I did this but didn’t feel any different. A knowledgeable friend then said to reduce the Adrenavive to a quarter and introduce pregnenalone, which I have done. It’s early days but I think it could be helping. I am usually shattered by the evening.

With your low morning cortisol, i assume you’ve been referred for a short synacthen test. The Endo usually sees it as black and white. You either have Addison’s disease or you don’t. My Endo (& I understand the nhs generally) does not recognise partial adrenal failure. So my Endo dismissed me without help. I understand that some are more helpful.

I hope this helps. It’s worth a try! Just get your finances sorted, Adrenavive is not cheap and Dr Myhill said it’s for life!

Kitten44 profile image
Kitten44 in reply toCornishChick

That's interesting. Just wondering if you have heard of the circadian T3 method for treating adrenals? It's meant to "reset" them so that adrenal support is not necessary. I'm thinking of trying myself, though I first need to find a reliable source of T3.

CornishChick profile image
CornishChick in reply toKitten44

I had but didn’t know mich about it. Have just read a bit and looks interesting. My worry would be not getting hold of T3, although Paul Robinson says you can use NDT. Do you use it? X

Kitten44 profile image
Kitten44 in reply toCornishChick

I'm just in the process of trying to source either of them and I've ordered the book, so will try it. I think it's worth a go. Particularly with the cost of adrenal cortex (I bought Thorne, as Adrenavive has been on "3-4 weeks" for some time), and I don't like the thought of having to be on it for life (though some say you can try to phase out after a few months/years to see if your adrenals have recovered). Now I need to get hold of some T3...

fizzygig profile image
fizzygig in reply toKitten44

Very interested in Paul Robinson's research. If adrenal test do not show Addisons/pituitary problems (still waiting for urgent endo appt) I will seriously consider trying this if I can get hold of NDT or T3. I now feel sure that my dysfunctional adrenals are related to my poorly treated Hashi's.

ter1461 profile image
ter1461

According to STTM treatment with adrenal cortex isn’t for life. Apparently up to two years.,.

Tinne profile image
Tinne

Pregnenolone inhibits the production of cortisol, so not good if you are already low in cortisol.

fizzygig profile image
fizzygig

Thanks

Cup-cake7 profile image
Cup-cake7

Hia may I ask how it is going, can relate. 🦋

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