Tgb/Tpo + suppressed TSH

[jib70]

I'm trying so hard to understand thyroid function and results, reading links here and googling. but still struggling.

If TSH is deemed "suppressed" but FT4 and FT3 are 'within range' and Tpo is high (well above range) with Tgb on low side of range does that clearly show a definite diagnosis? Should add this is all baseline, no treatment or supplementation.

Hope my question isn't too vague but just trying to get things straight in my head. Thanks.

[Angel_of_the_North]

High TPO antibodies would mean Autoimmune thyroid disease (Hashis). Low TSH with low normal Frees could mean central hypo. Low TSH with other normal TSH could mean that TSH hasn't risen yet after antibody attack. Don't expect NHS to treat with low TSH.

[jib70 in reply to Angel_of_the_North]

Thank you for explaining that. Do low TGB Abs mean much or are TPO antibodies the major factor? I'm in awe of people who understand all this, it's so complicated. Many thanks.