Having been "reasonably" well treated on 125mcg Levothyroxine for over a decade, a routine blood test showed that my TSH had crept up from the 1s to the 2s. I increased my dose to 150mcg and 3 to 4 months later I developed symptoms of hyperthyroid - anxiety, weight loss, sweating, shaking, diarrheoa, nausea, loss of appetite. I reduced my dose right back to 100mcg for a while before reverting back to 125mcg, but my symptoms remained the same (the anxiety being the worst symptom to manage).
A Medichecks blood test revealed that I was hypothyroid, results as follows
TSH 12.5 (0.27-4.20)
Free Thyroxine 11.9 (12.00-22)
T4 69.2 (59.00-154.00)
Free T3 2.86 (3.10-6.80)
Thyroglobulin 14.200 (0.00-115.00)
Thyroid Peroxidase 13.9 (0.00-34.00)
Active B12 133.000 (25.10-165.00)
Serum Folate 19.98 (2.91-50.00)
CRP High Sensitivity 0.74 (0.00-5.00
Ferritin 53.9 (13.00-150.00)
Since then I've increased my dose to 150mcg Mon, Wed, Fri, Sat and 125mcg Tues, Thurs, Sun, but my symptoms of anxiety etc haven't abated, even though my bloods are now heading in the right direction.
I've heard of Hashimoto's flare up and I wonder if this could be the cause of my symtoms even though my antibodies are hardly raised. Is it possible to have Hashimoto's even though my antibody levels are pretty low? Should a healthy person have antibodies of 0 or what?
I find it difficult to understand how to tell the difference between Hashimoto's and regular hypothyroidism, and if I have suffered a Hashimoto's flare up, should this just eventually subside spontaneously?
I'd be grateful for any thoughts and comments.