Hormones : Hi Over the past couple of days I have... - Thyroid UK

Thyroid UK

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Over the past couple of days I have been reading alot about progesterone / oestrogen on the forum.

Can anyone explain how it affects or is affected by thyroid?

I’m am hypo. I have always suffered from nasty peroids and pms. But the last 3 months ( diagnosed sept) have been awful. All symptoms have been worse and even had new ones.

Now wondering if this is thyroid related . Or both affecting each other.

Tsh 1

T4 21


11 Replies

Sorry I don't know sorry your feeling so rough

I have Graves and thought my levels were wrong as I was getting hot sweats etc back turns out it's the menopause. Would be interested in reply as I'm thinking of taking HRT but don't want to upset my thyroid


For full Thyroid evaluation you need TSH, FT4, TT4, FT3 plus TPO and TG thyroid antibodies. Plus vitamin D, folate, ferritin and B12.

Essential to test thyroid antibodies, FT3 and FT4, plus vitamins

Low vitamin levels are extremely common. Heavy periods are classic sign of being under medicated and often lead to low ferritin.

Ask GP to test vitamins and thyroid antibodies if not tested already

Private tests are available. Thousands on here forced to do this as NHS often refuses to test FT3 or antibodies


Medichecks Thyroid plus ultra vitamin or Blue Horizon Thyroid plus eleven are the most popular choice. DIY finger prick test or option to pay extra for private blood draw. Both companies often have money off offers.

All thyroid tests should ideally be done as early as possible in morning and fasting.

If on Levothyroxine, don't take in the 24 hours prior to test, and if on T3 don't take in 12 hours prior to test, delay and take straight after

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip, GP will be unaware)

If antibodies are high this is Hashimoto's, (also known by medics here in UK more commonly as autoimmune thyroid disease).

About 90% of all hypothyroidism in Uk is due to Hashimoto's. Low vitamins are especially common with Hashimoto's. Food intolerances too, especially gluten. So it's important to get tested.


Hi Dewberry1, I will try to answer your question about thyroid and progesterone/oestrogen.

There are strong inter-linked relationships between the ovarian, adrenal and thyroid systems (called the OAT axis) and balancing this axis is important for women to feel well. When medication alters one the organ's function it may lead to changes in the other two, i.e. when using thyroid medication it is not uncommon to see menstrual irregularities (ovarian hormones) and a reduced ability to deal with stress (adrenals).

The adrenal glands help to regulate stress, when too much cortisol is produced it will block progesterone receptors. Insufficient progesterone leads to an imbalance of oestrogen to progesterone giving rise to oestrogen dominance. Excessive oestrogen can lead to PMS, fibroids and pre-menopausal syndrome.

Adrenal fatigue will down-regulate thyroid function to conserve energy giving rise to secondary low thyroid function.

Dewberry1 in reply to Hidden

Thanks for your reply! That makes sense . Think I will see the doctor about sorting out hormone levels. I’m 27 I have many years of this to go still😩

I found this, it’s interesting


Gosh, when you fall into that mess how on earth do you get out of it!

Hidden in reply to FancyPants54

I was told to always start with your adrenals.

Hidden in reply to Mouldyoledoll

That's a really good article, thanks. Explains the connection much better than my attempt.

I am finding this link to be a great read, thank you for posting 🙂

Oh my God ... wow !

I get it !


That was very interesting! Answerd alot of my questions. Thanks!

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