Thyroid Hormones and Cardiac Arrhythmia

[helvella]

Johannes Wolfgang Dietrich says:

Our book "#Thyroid Hormones and Cardiac #Arrhythmia", including the articles from our Research Topic at Frontiers, is ready.

This new book is freely accessible and downloadable as a PDF or in EPUB format.

I've downloaded it but not yet opened it!

Topic editor:

Johannes Wolfgang Dietrich

Ruhr University Bochum

Bochum, Germany

Thyroid Hormones and Cardiac Arrhythmia

Preventive programs and the development of specific therapeutic measures have helped to significantly reduce the load of cardiovascular risk over the previous decades. This applies to both the epidemiology of cardiovascular disease on the population level and the prognosis of individual patients affected by chronic disease. However, a significant residual hazard, beyond traditional risk models, is persisting. This gap may be filled by recent research that rediscovered thyroid homeostasis as a major determinant of cardiovascular health. Current advances extend to large population-based studies that identified even variation of thyroid function within established population-based reference ranges to be significant risk factors for sudden cardiac death, malignant arrhythmia and other major endpoints. Hence, it is most timely that a “thyro-cardio centric” thematic topic has been selected for this journal in order to bring more insights into the effects of thyroid hormone levels on cardiac health and disease.

Thyroid hormones are among the key mediators affecting cardiovascular function. Although a close link between the thyroid and the heart is known for more than two centuries, it was the recent years that witnessed the emergence of a deeper physiological understanding of the thyro-cardiac axis. This progress was accelerated by the development of new methods in molecular biology, electrophysiology, systems medicine, computational statistics and bioinformatics. The exponential growth of the number of published papers on the thyroid-heart nexus underscores the dynamics of this still evolving interdisciplinary field. It is against this background that the editors have organized the scientific content of this special issue.

frontiersin.org/research-to...

[helvella]

Image of cover:

Image of cover

[rubyred in reply to helvella]

hiya, thanks for Posting. I started to read but it’s maybe a bit more than my mind can mange on a cold Sunday morning

I am taking T3 prescribed on NHS

Had my thyroid destroyed 11 years ago with RAI not well on thyroxine had no life for about 3 years responded super well to T3

Nov 2020 diagnosed with persistent AF I couldn’t feel the palpitations and they think I had it for some time without knowing and it caused enlarged heart, dilated cardiomyopathy, fluid on lungs and in tissues (9 pints) along with severe heart failure ejection fraction was 23%

I was very unwell

Cardiologist told me they know the brain and heart need t3 but they don’t know how much is too much Endocrine tried to take me off the T3 and I dug my heels in

Got the Di02 test and it confirmed I would

Never respond to thyroxine and the T3 was what was needed

During my ablation the cardiologist found an anomaly I have just 3 pulmonary veins rather than the usual 4 or 5 that most people have

I have 1 on the left and 2 on the right

The one pulmonary vein on the left is much thicker and more fibrous than someone who has the standard 2 veins

This was the cause of my AF as a person with just one pulmonary vein on the left is more susceptible to AF

I was right to dig my heels In cardiologists has also written to GP regarding genetic test and has confirmed T3 is the correct medication for me 😃

[helvella in reply to rubyred]

You absolutely were right.

Sometimes the actual cause, such as was found for you, isn't going to be obvious even to the true experts.

[Tythrop]

This is good stuff.Im too hypo Hashi at present to embark on learned reading , but am aware that GPs are told that too much thyroid medication can result in cardiac issues( my friend a retired high powered and open minded GP tells me this. ,) But given a choice between t4 health and risk of heart issues OR t4 ill health and less cardiac danger I know what I choose . Hypo thyroid life is one very hard to live

[Imaaan]

The exponential growth of the number of published papers on the thyroid-heart nexus underscores the dynamics of this still evolving interdisciplinary field.

^^^ I hope more advanced research is done in this area and hopefully in my lifetime God willingly. Over a decade ago, I had a doctor try to convince me that my tachycardia wasnt from anything but rather the way my heart always was. What a bizarre thing to say to a patient who never experienced tachycardia befor until then.

[Aurealis]

I’m not aware there are any Cardiologists specialising in treatment of patients with hypothyroidism and arrhythmia, or Endocrinologists specialising in treatment of patients with arrythmia and hypothyroidism - are there any?

[arTistapple in reply to Aurealis]

I would be surprised and pleased if this was a ‘thing’. It’s been known for years (as mentioned above). However very few cardiologists make any link, as far as I am aware, having lived it. As a routine test I was given it pre- heart attack, result sub clinical hypothyroid. Nobody paid any attention and nobody told me. Went on to have heart attack and angina pain for a further twenty years until finally levo was prescribed. Pain virtually gone. Hard to believe how it has been known and yet never acted on and thyroid specialists have real trouble calculating the help needed to deal with it too. What a mess. Can’t even understand their own information.

[tattybogle in reply to Aurealis]

don't know about 'specialist in both' ... but here is an article for GP's by two individuals who must have at least figured out how to talk to the 'other' specialist. gponline.com/endocrinology-... " Dr Iqbal is a specialist registrar in endocrinology and Dr Krishnan is a specialist registrar in cardiology, Liverpool".

In case you can't get access to read the text it's copied in this post, but for me the sign in page just disappears if i click on 'x' ..... healthunlocked.com/thyroidu.... gps-told-keep-tsh-0.5-2pmol-l-hypothyroidism-causes-raised-cholesterol-thyroid-disease-effects-on-heart-and-cardiovascular-system.

[Aurealis in reply to tattybogle]

thank you tattybogle

[Hidden]

I read down through the document, downloaded as a pdf, and noted with interest the relationship between low T3 and heart problems. Very useful, thanks

My local NHS hospital will not test for T3. The suppliers to the NHS unfairly charge too much for T3. A doctor at my GP practice refused to prescribe T3. He is not allowed to anyway due to the cost. So collectively do they risk damaging people’s hearts, especially those like me with the DI02 mutation who don’t convert T4 to T3 sufficiently?

My grandfather had a goitre, I believe due to hypothyroidism. Cause of death on his death certificate? Heart failure.

[Essexlil]

hi, my dear mum passed away 15 years ago from sudden cardiac death and undiagnosed arrhythmia. In her 30’s she was hyperthyroid. She was given radioactive iodine and was well until her mid 50’s. Her GP refused to refer her when her thyroid went underactive and it was years later she was diagnosed with underactive thyroid. She was never well and turned to armour thyroid. She was about 3 stones overweight by then and although she managed to loose some of this she was still overweight when she passed away aged 72 with a sudden cardiac arrest.

[helvella in reply to Essexlil]

It's tough at the time. And again when you find out more about why it might have happened.

Thanks for replying.

[Essexlil in reply to helvella]

yes it was a terrible shock and we never got to say goodbye. 15 years later and it seems not a lot has changed

[1tuppence]

Thank you helvella. I've saved this for reference.

[Sharoosz]

This is rather interesting. Has anyone heard of any link between thyroid, heart and emf (electro-magnetic frequency) sensitivity (also known as radiation sickness)? I.e., could having thyroid issues make one more EMF sensitive, leading to heart issues?