I am hypothyroid. I am on 100mcg levothyroxine and 60mcg liothyronine. My latest test results have me stumped,. Maybe someone can help me understand what is happening here:
TSH- 0.00uIU/ml (range .35-4.94)I took my last test last year in June the result was the same this was after being on T3 for about 3 months. My. T4 is within range 9.63pmol/L range- 9.01-19.05; last year it was 11.11; T3 is 4.58pmol/L range 2.63-5.70, last year it was 5.57. anti thyroglobulin ab 23.99iu/ml range <4.11 last year 11.23. anti-TPO >1000iu/ml, last year >1000 the range is <5.61.
I would appreciate your observations very much.
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Lebogang
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Do you have recent test results for vitamin D, folate, ferritin and B12?
Your antibodies are high this is Hashimoto's, (also known by medics here in UK more commonly as autoimmune thyroid disease).
About 90% of all hypothyroidism in Uk is due to Hashimoto's
You are taking a pretty high dose, yet results don't show over medicated
Really need to test vitamin D, folate, ferritin and B12. Always get actual results and ranges.
Post results when you have them, members can advise
Hashimoto's affects the gut and leads to low stomach acid and then low vitamin levels
Low vitamin levels affect Thyroid hormone working
Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten
According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find gluten free diet helps significantly. Either due to direct gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)
But don't be surprised that GP or endo never mention gut, gluten or low vitamins. Hashimoto's is very poorly understood
Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and slowly lower TPO antibodies
Ask GP for coeliac blood test first
Persistent low vitamins with supplements suggests coeliac disease or gluten intolerance
Low vitamins can cause low TSH when on high replacement dose
All thyroid tests should be done as early as possible in morning and fasting and don't take Levo in the 24 hours prior to test, and T3 twelve hours prior to test, delay and take straight after. This gives highest TSH, lowest FT4 and most consistent results
I dont think I have seen a tsh of 0.00 before ( I'm new to all this) doctors are often very switchy about anything less than 0.1 has anything been said about it and have they every investigated if your pituitary gland is behaving itself?
The time of day you test affects levels which are higher early and drop later and summer levels are usually higher than winter. TSH 0 is very suppressed, FT4 9.63 is low in range but that's not usual when you are taking proportionally so much more T3 than Levothyroxine. FT3 4.58 is good and only a little shy of the upper third of range.
Thyroid peroxidase and thyroglobulin antibodies are positive for autoimmune thyroid disease (Hashimoto's). There is no cure for Hashimoto's which causes 90% of hypothyroidism. Levothyroxine treatment is for the low thyroid levels it causes. Many people have found that 100% gluten-free diet is helpful in reducing Hashi flares, symptoms and eventually antibodies.
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