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Thyroid UK
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Advice on T3 dosing


Can anyone advise how I should start taking T3? I've ordered perrigo 5mcgs T3 tablets, and I'm currently taking thyroxine at 225mcgs per day. I'd like to reduce that and add in the T3. My last bloods are pasted below.

Tsh 0.014 (0.27-4.20)

Free thyroxine 24.2 (12-22)

Total thyroxine 151.0 (59-154)

Free T3 4.46 (3.10-6.80)

Reverse T3 36 (10-24)

Reverse T3 ratio 8.07 (15-75)

Thyroglobulin antibody 88.600 (0-115)

Thyroid peroxidase antibody 110 (0-34)

Active b12 256 (25.10-165)

Folate serum 19.36 (2.91-50.00)

25 oh vit d 71.9 (50-200)

CRP high sensitivity 11.4 (0-5)

Ferritin 92.6 (13-150)

3 Replies


FT4 is over range and rT3 is high so I would reduce Levothyroxine dose by 25mcg and initiate 2 x 5mcg T3. You can take the first 5mcg with Levothyroxine and the second at bedtime.

Thyroid peroxidase antibodies are positive for autoimmune thyroid disease (Hashimoto's). There is no cure for Hashimoto's which causes 90% of hypothyroidism. Levothyroxine treatment is for the low thyroid levels it causes. Many people have found that 100% gluten-free diet is helpful in reducing Hashi flares, symptoms and eventually antibodies.



B12, folate and ferritin are good.

VitD is just shy of replete which is >75 and optimal is 100-150 so I would supplement 5,000iu D3 for 4 weeks and then reduce to 5,000iu alternate days and retest in March. VitD should be taken 4 hours away from Levothyroxine and T3.

CRP is high which indicates inflammation somewhere in the body.


Thank you, I'll give that a try. I'm still supplementing my Vit D, so hopefully that will improve. They were dire previously. Could my allergies cause the high CRP reading? I've developed asthma in the last couple of years, so wondering if that might have some bearing on that?



Asthma can cause high CRP and I should think allergies probably do too.


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