Back with an update. I was gone for a while, and I wish I could say it was because all was perfect and I was doing better. That’s not the case. I hit rock bottom. This post will act as my journal trialing compounded T4 / T3. I hope it helps others and sheds some light on one of the lesser talked about treatment options. I’m happy to answer questions as I go.
My reverse T3 has consistently been very high at ~28 and my TSH is mildly high. FT3 and FT4 looked okay, but not great. After years of trying different meds and combos, I ended up back where I started — 125mcgs Synthroid. An increase in Synthroid makes me feel worse, probably due to the already sky-high RT3. Depression, a 40 pound weight gain at this point, and complete lack of energy have taken their toll. I knew I needed to try something else, but I was disillusioned by NDT and T3 not helping in the past. The ONLY thing I hadn’t tried is time-released compounded T3. I found a doc willingly to work with me to get this RT3 under control. The following is the plan we came up with:
I ditched the 125mcgs Synthroid and switched to a compounded time-released T4 / T3 combo. T4 = 15mcgs, T3 = 35mcgs. I am to take this combo twice daily, 12 hours apart. That equals a total of 30mcgs T4 and 70mcgs T3.
I started one week ago, and was overstimulated at first, so I took only one pill a day for the first week. Things have calmed down, so today I will add the second pill to take me up to the full dose.
So far, my energy has been better. My mood has improved some. My anxiety has increased, but is manageable. I’m irritable but keeping an eye on it. Appetite has increased some, but so has my activity level. Weight hasn’t changed. Too early to say if this will be a winning combo, but I’m cautiously optimistic. I was very afraid to make the switch, but I wasn’t living a fulfilled life. I was miserable and had to try.
Anyone have thoughts on this regimen? Specifically the dose? I’m just happy to have met a doctor who was willing to think outside the box. I will continue to update with my progress.