Havana2426 So there you are, your high antibodies mean that you are positive for autoimmune thyroid disease aka Hashimoto's which is where antibodies attack the thyroid and gradually destroy it. The antibody attacks cause fluctuations in symptoms and test results and this explains all the differences in your test results. Look at the difference here when on a higher dose of Levo your TSH is way over range and your free Ts have dropped right down:
FEB 2016 (125mcg levothyroxine/10mcg T3)
TSH 7.80 (0.2 - 4.2)
FREE T4 12.9 (12 - 22)
FREE T3 4.1 (3.1 - 6.8)
DEC 2015 (75mcg levothyroxine/10mcg T3)
TSH <0.02 (0.2 - 4.2)
FREE T4 20.3 (12 - 22)
FREE T3 5.2 (3.1 - 6.8)
When the antibodies attack, the dying cells dump a load of thyroid hormone into the blood and this can cause TSH to become suppressed and Free T4 and Free T3 to be very high or over range. You may get symptoms of being overmedicated (hyper type symptoms) to go along with these results that look as though you are overmedicated. Unless a GP knows about Hashi's and these hyper swings, then they panic and reduce or stop your thyroid meds.
The hyper swings are temporary, and eventually things go back to normal. Test results settle back down and hypo symptoms may return. Thyroid meds should then be adjusted again, increased until you are stable again.
Your endo doesn't appear to know or understand this and has messed around with your meds and seems to have made a right pig's ear of it.
With your August results of
AUG 2017 (150mcg levothyroxine)
TSH 0.03 (0.27 - 4.20)
FREE T4 21.1 (12 - 22)
FREE T3 4.0 (3.1 - 6.8)
it looks as though he panicked at your suppressed TSH. However, your FT4 is in range yet your FT3 is at the bottom of the range. Instead of reducing your Levo to 75mcg, what he should have done is reduced your Levo by 25mcg and given you back some T3, that would have reduced your FT4 a bit and increased your FT3.
Read and learn all about Hashi's, because your endo either doesn't understand it, doesn't know anything about it, or dismisses antibodies as being unimportant and you are going to have to help yourself.
You can help reduce the antibodies by adopting a strict gluten free diet which has helped many members here. Gluten contains gliadin (a protein) which is thought to trigger autoimmune attacks so eliminating gluten can help reduce these attacks. You don't need to be gluten sensitive or have Coeliac disease for a gluten free diet to help.
Supplementing with selenium l-selenomethionine 200mcg daily can also help reduce the antibodies, as can keeping TSH suppressed.
Gluten/thyroid connection: chriskresser.com/the-gluten...