Graves and taking NDT

[Maryloo03]

TSH 12.87

T4 free 8.3

T3 Free 2.74

[Maryloo03]

I am taking 120 NDT

[greygoose]

That doesn't look much like Grave's! Have you had your antibodies tested? I think we need a little more information, here!

[helvella Administrator in reply to greygoose]

Unless also taking Carbimazole?

[greygoose in reply to helvella]

Yes, as I said, we need more information.

[Clutter]

Maryloo03,

Graves doesn't go away after thyroidectomy or RAI. You are now very hypothyroid to have TSH 12.87. If TSH is 12.87 while you are taking 120mg NDT you are very undermedicated.

[Maryloo03 in reply to Clutter]

Should I add another tablet 60 mg?

[Clutter in reply to Maryloo03]

Maryloo03,

Not all at once. I'd add 30mg now and another 30mg two weeks later. Hold at 180mg for 6-8 weeks and retest.

[Maryloo03]

Hello Since our last conversation I have increased NDT to 150 and am ready to go to 180. Not feeling great .

TSH 11.19

T4 Free 9.7

T3 Free 3.27

[Clutter in reply to Maryloo03]

Maryloo03,

You are very undermedicated to have TSH 11.19 and that will be why you feel unwell. You haven't included lab ref ranges so I can't tell whether T4 and T3 are good or bad. When you are optimally dosed on NDT TSH will be low, <1.0, perhaps even suppressed and FT3 will be in the upper third of range.

I think you will need to be on 240 - 300mg before you are adequately dosed. I suggest you increase dose in 30mg increments at 2 week intervals and retest when you have been taking 240mg for 6 weeks.

[Maryloo03]

Thank you

TSH A11.19 0.32-5.04 mU/L

T4 Free A9.71 0.6-19.7 pmol/L

T3 Free 3.27 3.00-5.90 pmol/L

[Clutter in reply to Maryloo03]

Maryloo03,

FT4 isn't too bad and may even drop when you increase dose but FT3 is low. Aim for FT3 4.91 - 5.90.

[Maryloo03]

Thank you very much !!