Hello, I joined this support group on behalf of my sister who had Graves Disease and had her thyroid killed by Radioactive Iodine treatment. And now has Hypothyroidism. My sister became severely depressed and anxious over the last two years. She thought it was due to the extreme constant muscle and joint pain she has on her upper right side. It starts from her shoulder blade, directly in her shoulder, up her neck, face and head. When they couldn't find a cause they put her on antidepressants. A pain clinic put her on opiates and between the two drugs and no diagnosis her mental state has gotten worse. Now they say she has a personality disorder. She has tried to kill herself several times and starting last week she is now receiving Shock Therapy treatments for the depression. After doing research on the internet I've read that my sister's pain, anxiety, depression and mental breakdown can be caused by her thyroid disease. Her doctor's all say no because her thyroid test all comeback in the normal range. Do anyone of you have any experience in this area? I'm trying to keep my sister from losing her mind. She currently takes 125 mg of levothyroxine. She is 60 years old and we live in Seattle, WA.