My significant other has thyroid/front of neck pain only in the afternoons, coincides with difficulty concentrating. We both suspect he has Hashimoto's, with possible B12 deficiency (given the slightly elevated ALT). His doctor has agreed to test TPO antibodies soon, and also referred him to an ENT. I think the ENT is a waste of time given his results. What do you guys think? Has anyone experienced the afternoon only thyroid pain? My theory is perhaps his T4 synthesis peaks in the afternoon with corresponding peak of TPO and thyroglobulin expression, hence having pain only in the afternoons.
Ultrasound - perfectly normal, no inflammation, no nodules
TSH 4.3 mIU/l (range 0.3- 3.18)
Free T4 18.2 pmol/l (range 13.1-21.3)
Serum total protein 72 g/l (range 64-83)
Serum bilirubin 13 umol/l (range <21)
Serum ALT 46 IU/l (range 62-106)