Some members may be nervous of adding some T3 or taking T3 only or trying Natural Dessicated Thyroid (NDT) hormones when they are not seemingly getting any improvement when on levothyroxine.
Rumours seem to abound about T3 and I think most seem to come from the medical profession. I thought a few links/excerpts might be helpful:
In the email below, a physician wrote to a colleague of Dr. Lowe, arguing that no patient needs to use T3 and that T3 can be dangerous. Below the physician's email, Dr. Lowe replies to his arguments.
In my view, the recent four replacement therapy studies addressed patients on the left-side flange of the bell curve. The studies showed that replacement dosages are insufficient for relieving their hypothyroid symptoms. The studies are ipso facto evidence for a humanitarian imperative: that researchers and physicians now accommodate these patients’ need for dosages of thyroid hormone larger than those dictated by the concept of replacement therapies.
Presumptions of the Endocrinology Specialty: Instability of Desiccated Thyroid, Dangers of T3, and the Safety and Effectiveness of T4-replacement
The endocrinology specialty bases some of its most influential pronouncements on presumption—a basis that hardly justifies the certitude with which it expresses the pronouncements. Three presumptions appear to sustain the practice of T4-replacement. The presumptions are that desiccated thyroid is unstable, that T3 is troublesome and dangerous, and that T4-replacement is invariably safe and effective.
Instability of Desiccated Thyroid
Since the 1960s, the endocrinology specialty has advocated and even enforced only the use of T4-replacement in lieu of desiccated thyroid as a treatment for hypothyroidism. According to endocrinologists, the reason for this advocacy and enforcement is that the potency of desiccated thyroid is difficult to standardize. That is, the endocrinologists claim that too often, desiccated thyroid tablets don’t contain the amount of thyroid hormone reported on the label. They argue that the potency of synthetic T4 is more stable. That synthetic T4 products are more stable, however, is a mere presumption.
I can find no studies in which the stability of desiccated thyroid and synthetic T4 were compared. When I searched for studies in Medline, using the keywords "desiccated thyroid," "Armour," "stability," and "potency," I found no studies. But when I searched for "Synthroid" and either "stability" or "potency," I found two abstracts. In one, the authors state, "Levothyroxine tablets, 50 microg, have been marketed for many decades but have had numerous recalls due to degradation and failure to meet potency."