Hello. I was diagnosed overactive last summer. After a hosp appointment i was prescribed carbimazole 40mg. Oh my god after 7 days on it i had put on 7 pounds, i was falling asleep in work i was hugely emotional. I got referred again to the hosp after telling my gp i couldn't take it and couldn't function at work or home with 4 kids. Next i was put on propylthiouricil again after 10 days i was a sobbing dysfunctional mess. Again I was referred to hosp and spoke at length with the doc who then prescribed me just 5mg of carbimazole and referred me to the surgeon. In december my levels were 53 then last week were 72 so upon meeting the surgeon last thursday i agreed to a total thyroidectomy but because my levels are so high she's put me on 40mg of carbimazole. The op is booked for 22nd of Feb and i have to say i totally don't want to go through with it now. I also don't want the radioactive drink. I figure if the carbimazole is going to make me feel like crap anyway i may as well stick it out and try the block and replace therapy which i should have done to start with. I am so worried because even after 5 days i feel morose and getting foot and toe cramps and feel so miserable! It also seems to make my palpitations worse even though i'm on 60mg of propranalol. The thing is apart from the racing heart i have had no other symptoms. My hands don't shake, my eyes don't bulge, my neck looks normal, i don't sweat or have the runs. The only other thing is it's very hard to get up after kneeling or squatting. I feel so angry that this has come back after getting rid of it aged around 30 after about 3 years of having it. I am now nearly 45. So really this is me getting it off my chest because i'm so scared of trying to manage this illness!