I've posted before about problems I've been having with liothyronine over the past fifteen months. It's now become really serious for me. I have been on liothyronine since 2002 and had absolutely no problems with it until October 2014. I have experience what I believe is an allergic reaction to five batches of liothyronine over this period. I have had no problems with the other batches that I've had in this time.
I believe that since the UK manufacturer merged with companies in Europe in late 2013, they have changed the formula of the mixer. I believe that there is something in the new mixer which I am allergic to. I experience an increase in appetite, I can't get to sleep or stay asleep so become really tired and get all the problems associated with extreme tiredness. The worst problem is my eyes become really dry and incredibly sore. I've gained 17lbs over this time - my weight had been stable for years before this. When I change to a different batch it takes two to three weeks for most of the symptoms to go but my eyes remain sore for longer.
It's been very difficult and stressful to avoid these batches - my pharmacist has been very helpful.
Things came to a head this time because my pharmacist, in spite of trying for three weeks, was only able to obtain the one batch number of liothyronine that causes me the adverse reaction. As I ran out of liothyronine this morning, I telephoned every pharmacist I could find within fifteen miles of my home and finally managed to get hold of the previous batch that I'd been taking for the past six months. I was incredibly relieved but this batch expires less than two weeks after I finish it. I've found that this batch is a little under strength due to it's age and it does not fully control my hypo symptoms.
I am aware that only Uni Pharma have a licence to produce liothyronine in this country. I'm really stressing on what I can do as I think it either is now or very soon will be impossible to avoid batches with the new mixer.
One pharmacist I spoke to suggested I ask my GP to prescribe an unlicenced alternative - liothyronine in liquid form. Apparently, GPs can do this - although I was told many won't. I wondered if anyone knows anything about liquid liothyronine or of any alternative that I can get hold of preferably here in the UK but I would certainly consider buying elsewhere if I have to.
I did investigate buying T3 from abroad but the problem is that the companies that sell it in Europe are all now part of the Uni Pharma group and I would be paying for the same formula that I get here on the NHS and that I can't tolerate.
I did also look into buying from outside Europe. I read bad reports about both the supply situation and the variation in strengths of the lio. I did wonder about buying from the USA but was not sure if that is possible.
I have contacted both Uni Pharma and the defective drugs association in London. Uni Pharma are testing a couple of batches that I've sent them but they have ignored all of the many questions that I have asked them including, why was the formula changed. They won't admit that it has changed either.
The defective drugs association state that they, "routinely tested liothyronine towards the end of last year", it was acceptable. They don't state, and I've now asked, how old the lio was that they tested. They also state that some people are more sensitive to meds than others and everyone can't be accommodated. Whilst true, it ignores the fact that I've been on lio for thirteen years with no problems for first twelve years and that I can't stop taking it.
I'd be really grateful if anyone can offer any suggestions as I am really stressed out about this situation.