Ferritin very high, haemoglobin low. What does ... - Thyroid UK

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Ferritin very high, haemoglobin low. What does that mean

Butterflyaug52 profile image
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Latest blood test shows Ferritin 179 [13-150] ug/L range, but Haemoglobin concentration 123 [120-150] g/L. These seem contradictory. Can anyone suggest what this might indicate?

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Butterflyaug52
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helvella profile image
helvellaAdministratorThyroid UK

Have a read here:

en.wikipedia.org/wiki/Ferri...

There are several reasons for ferritin rising other than due to an excess of iron. So it is perfectly possible, even quite common, for ferritin and other iron levels to be apparently out of step with each other.

gabkad profile image
gabkad in reply to helvella

Why did I bother to write all that stuff when all you needed to do was link to wiki? Sheesh.

helvella profile image
helvellaAdministratorThyroid UK in reply to gabkad

Always good to have two viewpoints. :-)

gabkad profile image
gabkad in reply to helvella

Same viewpoint just different amount of words typed on keyboard. Or are you referring to the viewpoint of going to wiki? ;)

gabkad profile image
gabkad

I didn't check your previous posts, but have you been taking iron?

Is there any chance that you have a haemoglobinopathy? en.wikipedia.org/wiki/Hemog...

Are you vegan or vegetarian and possibly not consuming enough quality protein? If you are on a severe calorie restricted diet, the body will scavenge protein from muscle tissue. This will result in high ferritin because the body stores and recycles the iron from myoglobin. If you are consuming a low protein diet or a poor protein diet, then the same thing happens. Skeletal muscle mass decreases. Cardiac muscle tissue also decreases. Various problems will also cause high ferritin, like pancreatitis. Kidney problems will result in lowering of erthyropoeitin hormone levels even when a person is consuming enough iron to make for good hemoglobin levels.

Or do you have a chronic infection or other health problem? Immune system problems will result in high ferritin and low hemoglobin.

Sometimes the body will store iron in order to make it unavailable and prevent bacteria getting access to it.

There are hemoglobin abnormalities that prevent iron from being utilized.

Does your physician have anything to say about this? Are they going to be doing additional tests? There can be, as you see from above, many reasons and causes for your current situation.

Butterflyaug52 profile image
Butterflyaug52 in reply to gabkad

Thank you for the long reply. Will need to take these to the doctor then. Looks like no simple answer.

gabkad profile image
gabkad in reply to Butterflyaug52

Ah yes, I looked through your previous posts and this is about your wife. She sound extremely frail if her vertebra broke from going on a road trip.

Have bisphosphonate meds been optioned? Sometimes it's the best thing. Vertebral osteoporosis benefits from these drugs immensely. The pain from fractures is unremitting.

Butterflyaug52 profile image
Butterflyaug52 in reply to gabkad

You are correct. Since 2006 she's had quite a lot of bisphosphonate infusions, pamidronate and zoledronic acid. Indeed originally we put down hair loss and skin problems to them - but it seems clear these days that it isn't so. Nonetheless, they did make a difference to bone denity, but it is still bad and the spinal fracture last year occured when the density was beginning to clearly improve. (she couldn't tolerate oral bisphospohonates). She is just about to begin a course of parathyroid hormone injections.

gabkad profile image
gabkad in reply to Butterflyaug52

Why did you think her problem is thyroid related?

Butterflyaug52 profile image
Butterflyaug52 in reply to gabkad

This particluar item might not be - but she does also have practically the whole list of thyroid related problems. This is just the only item that blood tests show up as out of "normal" range!

gabkad profile image
gabkad in reply to Butterflyaug52

Chronic illness will suppress thyroid function:

thelancet.com/journals/lanc...

I suppose when it goes on for too long and metabolism is always slow, it will compromise healing of tissues. Lack of physical activity will result in muscle atrophy and joints will not be supported adequately..... hence painful to get around.

You could discuss with the doctor to trial a low dose T3 (5 mcg) because T4 is not being converted properly. It would not be entirely outrageous to try something at this dose. Taking a T4 would probably not do much.

Sugarplumb profile image
Sugarplumb

What a differance to me my ferritin is 7 and hemo 9 no wonder I feel ill x

Butterfly,

You may be low on B12 and Folate.

Blood cells need iron, folate and b12 to be formed.

Your iron is certainly high but not alarmingly high. If you are supplementing with iron stop and boost your b12 and folate levels

Heloise profile image
Heloise

Butterfly, this excerpt is from the Stop the Thyroid Madness Website for Optimal Lab Values:

If your ferritin is much higher, you have INFLAMMATION–the latter causes iron to be thrust into storage and inflammation is common with thyroid patients for a variety of reasons. In less common cases, higher ferritin can be from liver disease, alcoholism, diabetes, asthma, or some types of cancer. Men are generally higher than women without having the above problems. If ferritin is high along with a high % Sat and Serum iron, you may have hemachromatosis or a MTHFR defect. You should be off all iron for at least 12 hours before testing to see what your body is hanging onto, and 5 days to see your true iron levels.

stopthethyroidmadness.com/l...

Butterflyaug52 profile image
Butterflyaug52 in reply to Heloise

Thanks. Very interesting link I hadn't seen before. May well be inflammation, I can see.

daisyandrose profile image
daisyandrose

Can someone help with this. I have been dealing with my problems severely since 5 years ago. When I got tested they told me my ferretinlevel was 4! so I switched doctors and this new doctor immediately started me on injections. Whenit was getting to 80 and I was feeling great then once it reached 120 my doctor stopped. WE were both shocked that it worked and it was feeling better but then to her shock my iron level fell drastically again. So I have continuously on injectons along with B12 injections until she didnt feel right about it but by that point my levels were in the 300's. Today I got an update and my Ferretin is 337 and my hemoglobin is 4.9 I dont know what to do. I dont feel well I feel like I did when I had low ferretin levels my joints ache and my hair is shedding like crazy. Please help. Also my thyroid levels fluctuate between 2.5-4.95

humanbean profile image
humanbean in reply to daisyandrose

If your ferritin level dropped like a stone when you stopped getting injections, then it will almost certainly happen again. So I wouldn't worry too much about the high levels for the moment, it will probably drop soon enough.

If it really, really bothers you, the quickest way of lowering ferritin is to give blood.

This is a 2 year old post that you have replied to, and if you want to get more answers you would be best writing a post of your own with your questions and requests for advice and opinions. Many people ignore old posts.

To create your own post, look in the banner for an option which says "Write a post" and click on it.

Welcome to the forum. :)

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