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Xtandi
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Use of Rx drugs and botanical compounds to prevent chemo drug-resistance with Docetaxel.
Enzalutamide (
xtandi
) ADT (androgen deprivation therapy) First-line enzalutamide, docetaxel combination improves disease control in advanced prostate cancer February 15, 2019 https://www.healio.com/hematology-oncology/prostate-cancer/news/online/%7B6975a5a4-b882-4165-9963-f30e9d9dad8b%7D/first-line-enzalutamide-docetaxel-combination-improves-disease-control-in-advanced-prostate-cancer
Enzalutamide (
xtandi
) ADT (androgen deprivation therapy) First-line enzalutamide, docetaxel combination improves disease control in advanced prostate cancer February 15, 2019 https://www.healio.com/hematology-oncology/prostate-cancer/news/online/%7B6975a5a4-b882-4165-9963-f30e9d9dad8b%7D/first-line-enzalutamide-docetaxel-combination-improves-disease-control-in-advanced-prostate-cancer
chillpill7
in
Advanced Prostate Cancer
5 years ago
rising PSA on cabazitaxel !
He has had doxitaxel,
xtandi
, zytiga, Radium 223 ,docetaxel ( second time) and cabazitaxel. His PSA continues to increase and today after his second cabazitaxel it remains at 95. We are so concerned since there has not been any treatment that lowered his PSA.
He has had doxitaxel,
xtandi
, zytiga, Radium 223 ,docetaxel ( second time) and cabazitaxel. His PSA continues to increase and today after his second cabazitaxel it remains at 95. We are so concerned since there has not been any treatment that lowered his PSA.
joann48
in
Advanced Prostate Cancer
5 years ago
High T clinical trial update from a data point
The more interesting will be next three months as the HighT May resensitize the PC androgen receptors for the heavy smack down that the
Xtandi
is going to bring. After 3 years of ADT, highT felt great.
The more interesting will be next three months as the HighT May resensitize the PC androgen receptors for the heavy smack down that the
Xtandi
is going to bring. After 3 years of ADT, highT felt great.
Chugach
in
Advanced Prostate Cancer
5 years ago
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Taking these two drugs at the same time
What side effects do you experience when taking
xtandi
and Zuniga at the same time are they compounded?
What side effects do you experience when taking
xtandi
and Zuniga at the same time are they compounded?
Valree
in
Advanced Prostate Cancer
5 years ago
Long Road, and no legs to walk -
Then came
Xtandi
- (4) pills and after a month he developed horrific headaches, shortness of breath and weak legs. The Dr. had him stop for a week, then lowered the dosage. The symptoms stopped. After a month the symptoms came back and we're much worse.
Then came
Xtandi
- (4) pills and after a month he developed horrific headaches, shortness of breath and weak legs. The Dr. had him stop for a week, then lowered the dosage. The symptoms stopped. After a month the symptoms came back and we're much worse.
Trouble19
in
Advanced Prostate Cancer
5 years ago
Really wanting a break from the ADT drugs
Started
Xtandi
, and it has worked amazingly well. Been at PSA 0.00 for about 6 months now. After 2.5 years on ADT, Im really ready for a break from the drugs.
Started
Xtandi
, and it has worked amazingly well. Been at PSA 0.00 for about 6 months now. After 2.5 years on ADT, Im really ready for a break from the drugs.
joeguy
in
Advanced Prostate Cancer
5 years ago
Firmagon, Xtandi and Radiation
Zoladex 10,8mg 12 weekly for 5 years.Had a PETSCAN ,indicated no metestases outside the Prostate.Oncologist determined that due to rising PSA ,doubled in 3 Months. and became resistant to the Zoladex treatment.The Dr put me on Firmagon,initial triple shot, to be followed by monthly shot as well as
xtandi
Zoladex 10,8mg 12 weekly for 5 years.Had a PETSCAN ,indicated no metestases outside the Prostate.Oncologist determined that due to rising PSA ,doubled in 3 Months. and became resistant to the Zoladex treatment.The Dr put me on Firmagon,initial triple shot, to be followed by monthly shot as well as
xtandi
Andrevz
in
Advanced Prostate Cancer
5 years ago
Xtandi side effects and dose
Could anyone tell me if it's normal to have bone pains like my husband: back and ribs taking
Xtandi
and if anyone has experience of lowering the dose to 120 mg or 80mg? Could it help him? Would appreciate any reply feeling so worried.
Could anyone tell me if it's normal to have bone pains like my husband: back and ribs taking
Xtandi
and if anyone has experience of lowering the dose to 120 mg or 80mg? Could it help him? Would appreciate any reply feeling so worried.
JuanVV
in
Advanced Prostate Cancer
5 years ago
How can my Dad get his Calcium level up?
He is on
Xtandi
and Lupron. Thank you! Kimberly
He is on
Xtandi
and Lupron. Thank you! Kimberly
savingdaddy
in
Advanced Prostate Cancer
5 years ago
Appeal with the FAA
Was seen at Duke yesterday...Just for the record..my OC second letter pointed out
Xtandi
side effects were based on CT for MPC..and just approved for us guys in July have not yet reached that stage..Also the 1% seizure probability or less came from those with brain cancer, also side effects of this
Was seen at Duke yesterday...Just for the record..my OC second letter pointed out
Xtandi
side effects were based on CT for MPC..and just approved for us guys in July have not yet reached that stage..Also the 1% seizure probability or less came from those with brain cancer, also side effects of this
pilot52
in
Advanced Prostate Cancer
5 years ago
Failed Xtandi monotherapy, failed Lupron from very first injection, considering Zytiga or clone
Also was curious if any available information of current and upcoming
Xtandi
successors may work even though
Xtandi
has failed,,Alpa and Daro.
Also was curious if any available information of current and upcoming
Xtandi
successors may work even though
Xtandi
has failed,,Alpa and Daro.
Sxrxrnr1
in
Advanced Prostate Cancer
5 years ago
Re-sensitizing Zytiga and Xtandi
It seems that Niclosamide also has the potential to re-sensitize both enzalutamide (
Xtandi
) and abiraterone acetate (Zytiga). A few find that Zytiga and
Xtandi
doesn't work for them which is often due to the presence of the splice variant AR-V7.
It seems that Niclosamide also has the potential to re-sensitize both enzalutamide (
Xtandi
) and abiraterone acetate (Zytiga). A few find that Zytiga and
Xtandi
doesn't work for them which is often due to the presence of the splice variant AR-V7.
Terje
in
Advanced Prostate Cancer
5 years ago
Thinking about Starting Xtandi Question
My options at his time according to the Oncologist would be
Xtandi
or zapping the one left illium Met with 10 Radiation treatments. Now my Onco says to first try the
Xtandi
.
My options at his time according to the Oncologist would be
Xtandi
or zapping the one left illium Met with 10 Radiation treatments. Now my Onco says to first try the
Xtandi
.
tgrec
in
Advanced Prostate Cancer
5 years ago
Both apalutamide and enzalutamide succeed for metastatic hormone-sensitive prostate cancer (mHSPC) - enzalutamide not for high volume mets
New info presented this morning at ASCO - Enzalutamide (
Xtandi
) worked best in men with mHSPC with a [i]low[/i] volume of mets, and in men who did [i]not[/i] plan to have early docetaxel (which is probably much the same thing). Apalutamide worked well regardless of high or low volume of mets.
New info presented this morning at ASCO - Enzalutamide (
Xtandi
) worked best in men with mHSPC with a [i]low[/i] volume of mets, and in men who did [i]not[/i] plan to have early docetaxel (which is probably much the same thing). Apalutamide worked well regardless of high or low volume of mets.
Tall_Allen
in
Advanced Prostate Cancer
5 years ago
Longevity
I asked my Oncologist at MD Anderson what was the average lifespan for someone like me with stage 4 metastatic Prostate Cancer on
Xtandi
and Lupron. He said the average was 3-5. After a period depression from this news, would like to prove him 💀 DEAD wrong.
I asked my Oncologist at MD Anderson what was the average lifespan for someone like me with stage 4 metastatic Prostate Cancer on
Xtandi
and Lupron. He said the average was 3-5. After a period depression from this news, would like to prove him 💀 DEAD wrong.
TomNew62
in
Advanced Prostate Cancer
5 years ago
Why two tests?
The PSA has been slightly rising since it’s
Xtandi
nadir of 1.0 in September. They are having him stay on it while they do scans to check for progression. He had a full body CT scan with contrast last Monday and this coming Monday an NM bone scan.
The PSA has been slightly rising since it’s
Xtandi
nadir of 1.0 in September. They are having him stay on it while they do scans to check for progression. He had a full body CT scan with contrast last Monday and this coming Monday an NM bone scan.
Blair77
in
Advanced Prostate Cancer
5 years ago
Off BIRM for almost a month now. Wanted people who were following my "BIRM Journey" to know what's up. Stage 4~ Lupron,Xtandi,Xgeva 62y.o.
I started Fenben (hookworm med) on May 14th/2019 before I decided to take a "BIRM holiday"(on June 20th/2019). I Wanted to see if the Fenben (Joe's Protocol) would have any measurable effect on it's on. Wasn't on long enough for last PSA (which went up slightly from 2.39 to 2.69) to show any grand
I started Fenben (hookworm med) on May 14th/2019 before I decided to take a "BIRM holiday"(on June 20th/2019). I Wanted to see if the Fenben (Joe's Protocol) would have any measurable effect on it's on. Wasn't on long enough for last PSA (which went up slightly from 2.39 to 2.69) to show any grand
greatjohn
in
Advanced Prostate Cancer
5 years ago
Weak Legs
May call and see if I should cut back on dosage, if in fact the
Xtandi
is causing the weakness. Thanks
May call and see if I should cut back on dosage, if in fact the
Xtandi
is causing the weakness. Thanks
PSAontherun
in
Advanced Prostate Cancer
5 years ago
well...my PSA Graph Starts just after adding Xtandi to my Lupron....hoping for the opposite of what the trend says.
I started in appx June/July on
Xtandi
(added to Lupron)....and it's been an upward climb. It's like my PSA has helium in it. Nothing can hold it back...LOL.
I started in appx June/July on
Xtandi
(added to Lupron)....and it's been an upward climb. It's like my PSA has helium in it. Nothing can hold it back...LOL.
greatjohn
in
Advanced Prostate Cancer
5 years ago
Good News
Diagnosed in 2011 had prostatectomy radiation chemo, lupron ,
Xtandi
,with minimal results. I began LU 177 trial four months ago. PSA dropped from 1460 to 277. My scans are less impressive. I feel good. Two out of three works for me. D
Diagnosed in 2011 had prostatectomy radiation chemo, lupron ,
Xtandi
,with minimal results. I began LU 177 trial four months ago. PSA dropped from 1460 to 277. My scans are less impressive. I feel good. Two out of three works for me. D
pinejogave
in
Advanced Prostate Cancer
5 years ago
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