Experiences with

Thyrotropin-releasing hormone

Summary Paragraph: The study examines testosterone recovery (TR) in prostate cancer patients undergoing androgen deprivation therapy (ADT) in conjunction with radiotherapy, as assessed across multiple randomized trials by the MARCAP Consortium. Variabilities in TR were identified based on ADT

Well, I have not searched about this for long, but while I wait to see if estrogen patches will be approved in europe for metastatic cancer, I am having doubts about switching from triptorelin (which did and is still doing its job) to relugolix. I know my MO first instinct will be saying "if it's working

"Compliance" with meds taking and timing is a big issue, as we all know. And research shows that especially with the elderly, compliance to meds regimes and timings by day and by week is difficult to follow. And the consequences are not good. When one is on doublet therapy (whether or not one had also

Hi all, Okay my first post… always suffered from painful periods remember being sent to the medical room at school for belly aches. Yet after having my daughter at 24 I became anaemic from months of bleeding and have suffered since. Been on iron supplements for the past 20 years. The odd internal

[i]This recent research paper in Nature is potentially ground-breaking for the understanding of essential mechanisms involved with bone health. It's findings are related to hormonal changes during the start of mid-pregnancy lactation and early newborn nurturing that could possibly lay the foundation

Hi ladies I am hopeless and devastated so down spirited I found many useful posts here thought I share my concerns with you if anyone have similar experiences to share I really appreciate although my case might be very rare due to having adenomyosis removed- normally its being treated only with

Unless I missed it, I haven't seen a post about the anticipated-this-fall results of the PATCH Study. I just noticed that it was reported out at the ESMO meeting a couple of weeks ago. They noted "key takeaways" to include: **Transdermal estradiol is as effective as LHRH agonist and there is no detriment

A potentially important issue for some people. And one that is 100% ignored when dentists say we should not rinse after brushing. Even if we do rinse after some time, it is likely that we will swallow some of the calcium ingredients (if our toothpaste contains any). Despite being written as a paediatric

If you search this forum, you can find 52 posts which mention "cataract" - and several gave rise to significant discussions. Search if you wish: https://healthunlocked.com/thyroiduk/search/posts?query=cataract I'm not sure how much "proof" this paper provides of a link. But it certainly points a finger

Two years in to my de novo high volume metastatic prostate cancer diagnosis, I am pleased to report excellent results so far with triplet therapy (Docetaxel chemo completed, Abiraterone ARPI, Firmagon/Degarelix GnRH antagonist as ADT). However I would be grateful for any advice today. My ALT has fallen

Like most documents, this has strengths and weaknesses. You might find it easier to follow than some. Though some of it really is quite hard for those not already familiar with thyroid issues. Or more up-to-date (it was published this year - 2024). And it might provide some useful and quotable

A rather disappointing paper. First, the full paper is, as so often, behind a paywall. Also, because the the paper doesn't come out with a clear "Yes, the tests are wonderful and reliable." It is quite clear that there is sufficient uncertainty to question all results from these tests. We have had

Hi just after some help please. I have had suppressed TSH levels since 2010, apart from a blip in 2014 when it was 2 pmol/l. (range is 0.35 to 4.7. ). My level has been consistently low at 0.02 pmol/l from 2018 to 2024. My T4 has been in range over the years ( 7.8 to 21) however my T3 was raised at

Hi, First round of IVF and had eggs collected yesterday. I have all the risk factors for OHSS, but we are mitigating as much as possible (gnrh agonist trigger, freezing eggs, Cabergoline, clexane and gnrh antagonist for the next few days). For those who have had OHSS, how long after the collection did

Advice, personal experiences, and comments most welcome.... Apologies for the long post, but it covers my story so far to provide context. So.... probably the same story as many of you here: I have probably had endo for a very very long time, frequent visits to doctors re bleeding and pain etc. to be

there is /was so much to think about when I got the Gleason 9 diagnosis after 18 months of being told don’t worry it not high risk and so had failed HIFU. Stupid of me ! I got, with great difficulty a DEXA scan one month after starting LHRH agonist goserelin. No one told me I needed it, and given

Brand new paper from Johannes Dietrich (one of diogenes' group) and others. [i]What is takotsubo cardiomyopathy?[/i] [i]British Heart Foundation[/i] https://www.bhf.org.uk/informationsupport/conditions/cardiomyopathy/takotsubo-cardiomyopathy [i]Takotsubo syndrome outcomes predicted by

Hi all, I was diagnosed with stage 4 endometriosis in 2016 and underwent excision surgery. After surgery I still struggled with pain however went on to try and start a family. We have been incredibly fortunate and have 3 children (this wasn’t without loss). My periods always returned very quickly

I had a lap investigation in october. the surgeon told me post op that she couldn’t remove any endo and she suggested GNRH injections. I had my follow up appointment with the consultant yesterday who thought that the surgeon had removed the endo, when i told her they hadn’t she said i needed a 2nd op

So… im coming off hrt after being on it 16 years due to being diagnosed with endo , and so im going through menopause like symtoms at the age of 58. My gynocologist has also said i may need to consider going on Gnrh analogue, which i really dont want to, due to all the horrible side effects . My grandma